Retrospective evaluation of plasma cholesterol concentration in septic dogs and its association with morbidity and mortality: 51 cases (2005–2015)

Retrospective evaluation of plasma cholesterol concentration in septic dogs and its association... AbbreviationsTNFtumor necrosis factorWRSWilcoxon rank‐sumIntroductionSepsis is a common cause of morbidity and mortality in both human and veterinary populations. The prevalence of sepsis in veterinary medicine has not been clearly defined, though studies have suggested rates of 3 cases per 1,000 population with an average mortality rate of approximately 28% in people. Mortality rates in dogs are reported to range from 21% to 68%. Research in the past decade has shown that sepsis is becoming increasingly prevalent within the human medical field, and between 2000 and 2008, the number of hospital stays due to sepsis increased more than doubled. Treatment of sepsis requires significant financial investment in both people and animals. Studies investigating the cost of sepsis in people have suggested estimates of $22,000–$50,000 per episode. Although average costs have not been published in veterinary medicine, it is generally accepted that appropriate treatment for septic dogs and cats remains a considerable financial burden for owners. With the significant mortality risk of sepsis, the intricacy of the syndrome itself, and the high cost to the owner, much research in the veterinary field has been directed toward identifying specific and reliable prognostic markers.Hypocholesterolemia as a prognostic marker in septic patient populations has http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Veterinary Emergency and Critical Care Wiley

Retrospective evaluation of plasma cholesterol concentration in septic dogs and its association with morbidity and mortality: 51 cases (2005–2015)

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Publisher
Wiley
Copyright
Copyright © 2018 Veterinary Emergency and Critical Care Society
ISSN
1479-3261
eISSN
1476-4431
D.O.I.
10.1111/vec.12705
Publisher site
See Article on Publisher Site

Abstract

AbbreviationsTNFtumor necrosis factorWRSWilcoxon rank‐sumIntroductionSepsis is a common cause of morbidity and mortality in both human and veterinary populations. The prevalence of sepsis in veterinary medicine has not been clearly defined, though studies have suggested rates of 3 cases per 1,000 population with an average mortality rate of approximately 28% in people. Mortality rates in dogs are reported to range from 21% to 68%. Research in the past decade has shown that sepsis is becoming increasingly prevalent within the human medical field, and between 2000 and 2008, the number of hospital stays due to sepsis increased more than doubled. Treatment of sepsis requires significant financial investment in both people and animals. Studies investigating the cost of sepsis in people have suggested estimates of $22,000–$50,000 per episode. Although average costs have not been published in veterinary medicine, it is generally accepted that appropriate treatment for septic dogs and cats remains a considerable financial burden for owners. With the significant mortality risk of sepsis, the intricacy of the syndrome itself, and the high cost to the owner, much research in the veterinary field has been directed toward identifying specific and reliable prognostic markers.Hypocholesterolemia as a prognostic marker in septic patient populations has

Journal

Journal of Veterinary Emergency and Critical CareWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

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