Prognostic value of pathologic grade for patients with oral squamous cell carcinoma

Prognostic value of pathologic grade for patients with oral squamous cell carcinoma INTRODUCTIONOral squamous cell carcinoma (OSCC) is one of the most common cancers. However, despite surgery with or without combined chemoradiotherapy, the 5‐year survival rate and recurrence rate remain poor (Wang et al., ; Xu, Wang, Yuan, Feng, & Han, ). Thus, many studies have focused on prognostic factors and their reliability for use with OSCC, such as clinical stage, histological signs, and pathologic grade (Meng et al., ; Montes et al., ; Morris, Patel, Shah, & Ganly, ; Philip & James, ; Sagheb, Sagheb, Taylor, Al‐Nawas, & Walter, ; Valentini et al., ; Yang et al., ). Among these factors, the prognostic value of pathologic grade is attracting increasing interest, but not without controversy.In most researches, the pathologic grade was estimated by the histopathological grading system proposed by the World Health Organization (WHO) (Amin et al., ; Barnes, Eveson, Reichart, & Sidransky, ; Broders, ). In this study, the pathologic grade was also evaluated by this method. However, the conventional classification is suggested by many authors that it cannot predict the prognosis of OSCC independently; furthermore, similar results were observed in our previous studies (Feng et al., ; Niu et al., ). Therefore, new methods about pathologic grade were recently proposed, and studies regarding the feasibility of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Oral Diseases Wiley

Prognostic value of pathologic grade for patients with oral squamous cell carcinoma

Loading next page...
 
/lp/wiley/prognostic-value-of-pathologic-grade-for-patients-with-oral-squamous-VRWC6PkyX3
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
Copyright © 2018 John Wiley & Sons A/S. Published by John Wiley &Sons Ltd
ISSN
1354-523X
eISSN
1601-0825
D.O.I.
10.1111/odi.12727
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONOral squamous cell carcinoma (OSCC) is one of the most common cancers. However, despite surgery with or without combined chemoradiotherapy, the 5‐year survival rate and recurrence rate remain poor (Wang et al., ; Xu, Wang, Yuan, Feng, & Han, ). Thus, many studies have focused on prognostic factors and their reliability for use with OSCC, such as clinical stage, histological signs, and pathologic grade (Meng et al., ; Montes et al., ; Morris, Patel, Shah, & Ganly, ; Philip & James, ; Sagheb, Sagheb, Taylor, Al‐Nawas, & Walter, ; Valentini et al., ; Yang et al., ). Among these factors, the prognostic value of pathologic grade is attracting increasing interest, but not without controversy.In most researches, the pathologic grade was estimated by the histopathological grading system proposed by the World Health Organization (WHO) (Amin et al., ; Barnes, Eveson, Reichart, & Sidransky, ; Broders, ). In this study, the pathologic grade was also evaluated by this method. However, the conventional classification is suggested by many authors that it cannot predict the prognosis of OSCC independently; furthermore, similar results were observed in our previous studies (Feng et al., ; Niu et al., ). Therefore, new methods about pathologic grade were recently proposed, and studies regarding the feasibility of

Journal

Oral DiseasesWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off