Despite improvements in intensive care support, congenital diaphragmatic hernia (CDH) is still a life‐threatening anomaly. The prevalence of the disease is 1:2,000–1:3,000 live births and the mortality rate is high (30–40%). Although many factors play role in the prognosis of CDH, the major determinant of survival is pulmonary hypoplasia and related pulmonary hypertension (PH).Displacement of abdominal organs to the thoracic cavity due to the diaphragm defect causes pulmonary hypoplasia and abnormality in pulmonary vascular structure by affecting lung development in the intrauterine period. The degree of PH as a result of abnormal heart and lung development determines the severity and prognosis of CDH. Progressive increase in pulmonary artery pressure (PAP), right ventricular (RV) failure and concomitant left ventricular (LV) dysfunction are associated with mortality in PH. The degree of PH and persistent PH (PPH) can be determined on conventional echocardiography. There are limited studies on the echocardiographic prognostic indices of CDH in infants. The aim of this study was therefore to investigate whether LV diameter and non‐invasive predicted PAP could be used to predict outcome in CDH.MethodsThis retrospective study was performed in January 2012–December 2016 in patients with CDH. The exclusion criteria were birth before 36 weeks of gestation,
Pediatrics International – Wiley
Published: Jan 1, 2018
Keywords: ; ;
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