Sir: Chordoma is a rare malignant tumour demonstrating notochordal differentiation. It almost invariably arises in the axial skeleton; however, rare examples of primary extra‐axial chordomas have been reported. We describe herein, for the first time to our knowledge, a primary conventional chordoma arising in the synovium of the knee joint.A 62‐year‐old female was admitted with swelling of the left knee and pain. Magnetic resonance imaging (MRI) demonstrated a large mass filling the knee joint, invading the distal epiphysis and the diaphysis of the femur. Erosions in the lateral condyle of the tibia were observed (Figure A). The tumour measurement was 168 × 105 × 93 mm.(A) Sagittal proton density fat suppressed sequence image shows a large intra‐articular lesion involving the knee joint. There is no involvement of the underlying bone. (B,C) Grossly, the tumour is lobulated, covered by overlying synovium. On cross‐section it is homogeneous, white–grey and solid.The patient underwent surgery and an attempted gross total resection was performed, but the tumour could not be removed totally.Six months postoperatively a complete MRI was performed of the whole axial and appendicular skeleton and the left knee joint. The MRI of the spine did not show any evidence of a primary
Histopathology – Wiley
Published: Jan 1, 2018
Keywords: ; ; ;
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