Prevalence of GB virus type C/hepatitis G virus RNA and of anti‐E2 in individuals at high or low risk for blood‐borne or sexually transmitted viruses: evidence of sexual and parenteral transmission

Prevalence of GB virus type C/hepatitis G virus RNA and of anti‐E2 in individuals at high or... BACKGROUND: The first epidemiologic evidence of GB virus type C (GBV‐C)/hepatitis G virus (HGV) infection showed a high prevalence of asymptomatic carriers in blood donors and in populations at risk for blood‐borne viruses. However, by using only viral RNA polymerase chain reaction, those studies underestimated the true spread of GBV‐C/HGV infection. The combined detection of GBV‐C/HGV RNA and of anti‐E2 (which reflects recovery from infection) is necessary to define accurately the prevalence of GBV‐C/HGV. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Transfusion Wiley

Prevalence of GB virus type C/hepatitis G virus RNA and of anti‐E2 in individuals at high or low risk for blood‐borne or sexually transmitted viruses: evidence of sexual and parenteral transmission

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Publisher
Wiley
Copyright
Copyright © 1999 Wiley Subscription Services
ISSN
0041-1132
eISSN
1537-2995
D.O.I.
10.1046/j.1537-2995.1999.39199116899.x
Publisher site
See Article on Publisher Site

Abstract

BACKGROUND: The first epidemiologic evidence of GB virus type C (GBV‐C)/hepatitis G virus (HGV) infection showed a high prevalence of asymptomatic carriers in blood donors and in populations at risk for blood‐borne viruses. However, by using only viral RNA polymerase chain reaction, those studies underestimated the true spread of GBV‐C/HGV infection. The combined detection of GBV‐C/HGV RNA and of anti‐E2 (which reflects recovery from infection) is necessary to define accurately the prevalence of GBV‐C/HGV.

Journal

TransfusionWiley

Published: Jan 1, 1999

References

  • Sequence and genomic organization of GBV‐C: a novel member of the flaviviridae associated with human non‐A‐E hepatitis
    Leary, TP; Muerhoff, AS; Simons, JN
  • Detection of GBV‐C RNA in patients with non‐A‐E fulminant hepatitis by reverse‐transcription polymerase chain reaction
    Kanda, T; Yokosuka, O; Ehata, T
  • Prevalence of hepatitis G virus RNA in French blood donors and recipients
    Loiseau, P; Mariotti, M; Corbi, C
  • An ELISA for detection of antibodies to the E2 protein of GB virus C
    Dille, BJ; Surowy, TK; Gutierrez, RA
  • Infection by hepatitis C virus through contaminated intravenous immune globulin: results of a prospective national inquiry in France
    Lefrere, JJ; Loiseau, P; Martinot‐Peignoux, M
  • Hepatitis C virus: new diagnostic tools
    Lefrere, JJ.
  • Hepatitis C virus: new diagnostic tools
    Wolfe, L; Tamatsukuri, S; Sayada, C; Ryff, JC.
  • BMDP statistical software

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