Prevalence and characteristics of human parechovirus and enterovirus infection in febrile infants

Prevalence and characteristics of human parechovirus and enterovirus infection in febrile infants Fever without source (FWS) in neonates–young infants up to 3 months of age is a potentially life‐threatening illness because the risk of severe bacterial infection (SBI) at this age is higher than that in older children. Today, the epidemiology of FWS during early infancy has changed because of intrapartum antibiotic prophylaxis for group B streptococcus and the introduction of Haemophilus influenzae type b and pneumococcal vaccination. During the past decade, detection of various viruses has improved by virtue of the development of new molecular techniques and the availability of monoclonal antibodies for many viral species. Furthermore, the FWS etiology during early infancy is being gradually elucidated.Human parechovirus (HPeV) and human non‐polio enterovirus (EV) are important causes of viral infection and meningitis in neonates and young infants. The clinical spectrum of HPeV and EV infections varies from fever to severe systemic disease, including sepsis and meningoencephalitis, which might engender severe neuropsychological sequelae. Several studies have specifically examined HPeV and EV prevalence in European countries and the USA, but their prevalence and clinical characteristics remain largely unknown in Asian countries.This study was conducted to investigate the prevalence of HPeV‐ and EV‐associated infection in a cohort of unselected pediatric patients aged <3 months old http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatrics International Wiley

Prevalence and characteristics of human parechovirus and enterovirus infection in febrile infants

Loading next page...
 
/lp/wiley/prevalence-and-characteristics-of-human-parechovirus-and-enterovirus-pID9hARj2e
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
Copyright © 2018 Japan Pediatric Society
ISSN
1328-8067
eISSN
1442-200X
D.O.I.
10.1111/ped.13467
Publisher site
See Article on Publisher Site

Abstract

Fever without source (FWS) in neonates–young infants up to 3 months of age is a potentially life‐threatening illness because the risk of severe bacterial infection (SBI) at this age is higher than that in older children. Today, the epidemiology of FWS during early infancy has changed because of intrapartum antibiotic prophylaxis for group B streptococcus and the introduction of Haemophilus influenzae type b and pneumococcal vaccination. During the past decade, detection of various viruses has improved by virtue of the development of new molecular techniques and the availability of monoclonal antibodies for many viral species. Furthermore, the FWS etiology during early infancy is being gradually elucidated.Human parechovirus (HPeV) and human non‐polio enterovirus (EV) are important causes of viral infection and meningitis in neonates and young infants. The clinical spectrum of HPeV and EV infections varies from fever to severe systemic disease, including sepsis and meningoencephalitis, which might engender severe neuropsychological sequelae. Several studies have specifically examined HPeV and EV prevalence in European countries and the USA, but their prevalence and clinical characteristics remain largely unknown in Asian countries.This study was conducted to investigate the prevalence of HPeV‐ and EV‐associated infection in a cohort of unselected pediatric patients aged <3 months old

Journal

Pediatrics InternationalWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off