INTRODUCTIONAtherosclerotic coronary artery disease (CAD) is a complex and chronic inflammatory disease. Patients with left main disease (LMD) and/or three‐vessel coronary disease (3VD) are at the highest risk for cardiovascular adverse events in CAD . Previous studies have reported various clinical and anatomical scores, including SYNTAX score, residual SYNTAX score, and SYNTAX score II, that are useful for stratifying high‐risk patients. However, it is difficult to easily apply them in clinical settings because of complexity. Notably, it is essential to find readily available clinical or laboratory markers that predicate future clinical outcomes in LMD/3VD. Acute myocardial infarction (AMI) induces acute inflammatory and stress responses that are characterized by increased mobilization of leukocytes in the necrotic area .Circulating white blood cell (WBC) counts have been established as a marker of inflammation, and previous studies have reported that the WBC count recorded within 24 hr of admission to hospital is a strong and independent predictor of mortality and major adverse events for AMI patients . Neutrophilia reflects the systemic inflammatory status. Similarly, a low lymphocyte count is significantly and independently associated with increased cardiovascular morbidity and mortality .Recently, the circulating neutrophil to lymphocyte ratio (NLR) has emerged as a potent composite
Catheterization and Cardiovascular Interventions – Wiley
Published: Jan 15, 2018
Keywords: ; ; ;
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