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J. Kovacs, H. Kovacs, I. Könyves, J. Csaszar, T. Vajda, H. Mix (1961)
Chemical Studies of Polyaspartic Acids1Journal of Organic Chemistry, 26
R. Schwyzer, W. Rittel, H. Kappeler, B. Iselin (1960)
Synthese eines Nanadeka‐peptides mit hoher corticotroper WirksamkeitAngewandte Chemie, 72
J. Kovacs, M. Ceprini, C. Dupraz, G. Schmit (1967)
Pentachlorophenyl esters of n-carbobenzoxy-l-amino acids.The Journal of organic chemistry, 32 11
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Cleavage of N-Carbobenzoxy Groups by dry Hydrogen Bromide and Hydrogen ChlorideJournal of Organic Chemistry, 17
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Ultracentrifugation in Biochemistry, Academic Press
V. Bruckner, M. Kajtár, J. Kovacs, H. Nagy, J. Wein (1958)
Synthese des immunspezifischen, polypeptid-artigen haptens der anthrax-subtilis bacillengruppe. Ein synthetischer beweis der konstitution der natürlichen polyglutaminsäuren☆Tetrahedron, 2
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Synthesis of Peptide Polymers with Repeating SequencesJournal of the American Chemical Society, 85
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A New Method of Forming Peptide BondsJournal of the American Chemical Society, 77
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Base-catalyzed Formation of Cyclic Compounds from Poly--benzyl-L-aspartate and Poly--benzyl-L-glutamateJournal of the American Chemical Society, 85
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Une nouvelle méthode de synthèse peptidiqueHelvetica Chimica Acta, 34
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ACYLALKYLCARBONATES AS ACYLATING AGENTS FOR THE SYNTHESIS OF PEPTIDESJournal of the American Chemical Society, 73
K. Stich, H. Leemann (1963)
Kinetische Studie zur Aminolyse von «aktiven Estern» bei der Peptidsynthese. 3. Mitteilung über chemische Struktur und UV.-SpektroskopieHelvetica Chimica Acta, 46
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Who is a D.A.
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Sequence peptide polymers. I. Polymers based on aspartic acid and glycine.Journal of the American Chemical Society, 89 4
J. Kovacs, R. Giannotti, A. Kapoor (1966)
Polypeptides with Known Repeating Sequence of Amino Acids. Synthesis of Poly-L-glutamyl-L-alanyl-L-glutamic Acid and Polyglycylglycyl-L-phenylalanine through Pentachlorophenyl Active Ester1Journal of the American Chemical Society, 88
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Imides from Asparagine and Glutamine. II. α-Aminoglutarimide1Journal of the American Chemical Society, 79
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Synthesis of polypeptides with known repeating sequence of amino acids.Journal of the American Chemical Society, 87 1
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Synthese von Zwischenprodukten für den Aufbau corticotrop wirksamer Polypeptide III. Das Decapeptid H·Ser‐Tyr‐Ser‐Met‐Glu‐His‐Phe‐Arg‐Try‐Gly·OH und einige seiner DerivateHelvetica Chimica Acta, 44
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t-Butyl Esters of Amino Acids and Peptides and their Use in Peptide Synthesis1Journal of the American Chemical Society, 82
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On the optical purity of peptide active esters prepared by N,N'-dicyclohexylcarbodiimide and "complexes" of N,N'-dicyclohexylcarbodiimide-pentachlorophenol and N,N'-dicyclohexylcarbodiimide-pentafluorophenol.Journal of the American Chemical Society, 89 1
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D. DeTar, T. Vajda (1967)
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Co-operative Effects of Functional Groups in Peptides. I. Aspartyl-serine DerivativesJournal of the American Chemical Society, 84
To make a comparison of some of the various polymerization methods, poly‐γ‐D‐and L‐glutamylglycine were synthesized through the mixed anhydride, carbodiimide, and pentachlorophenyl active ester methods. This last method proved to be best, on the basis of weight‐average molecular weights (&Mmacr;w). A detailed study was also carried out to determine the optimum conditions for this method. The &Mmacr;w, values of the polymers were determined by the sedimentation equilibrium method; it was found that the pentachlorophenyl active ester gave &Mmacr;w values of up to 11, 500 but the mixed anhydride and carbodiimide methods gave &Mmacr;w, values of only about 1000. Tests with rabbit antianthrax immune serum showed that neither D‐ nor L‐isomer precipitated with the antiserum, but that, both were able to inhibit the precipitation of the antiserum by anthrax polypeptide. In addition, the D‐polymer gave more inhibition than the L, which would indicate a specificity of the antibody for D‐glutamic acid residues.
Biopolymers – Wiley
Published: Jun 1, 1968
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