Photoaggravated allergic contact dermatitis and transient photosensitivity caused by methylisothiazolinone

Photoaggravated allergic contact dermatitis and transient photosensitivity caused by... Photoaggravation in cases of sensitization to methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) has been reported previously (, ). Here, we describe 10 patients, 7 from Belgium and 3 from France, suffering from photoaggravated dermatitis, in some cases followed by transient photosensitivity, after sensitization to these biocides.Patients and MethodsTen patients, 5 men and 5 women, with a median age of 49.5 years, were investigated in Bordeaux, Marseille, and Toulouse (1 patient each; patients 1–3), in Antwerp (n = 4; patients 4–6 and patient 10) and in Leuven (n = 3; patients 7–9) between January 2012 and February 2017. All had presented with skin lesions in a photodistributed pattern, or showed more pronounced lesions on ultraviolet (UV)‐exposed skin regions, often involving the face and/or the back of the hands. Seven of them, upon referral to the patch test clinic, gave a clear history of consistent photoaggravation whenever their dermatitis was exposed to sunlight. In others (e.g. patient 2) the relative photodistribution of the skin lesions became apparent only during further follow‐up, when UV‐exposed skin became more prominently affected. For patients 7 and 9, no information had been documented regarding subjective symptoms upon sun exposure. However, also in these 2 patients, UV‐exposed skin areas were more strongly affected. Occasionally (patients http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Contact Dermatitis Wiley

Photoaggravated allergic contact dermatitis and transient photosensitivity caused by methylisothiazolinone

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
ISSN
0105-1873
eISSN
1600-0536
D.O.I.
10.1111/cod.12926
Publisher site
See Article on Publisher Site

Abstract

Photoaggravation in cases of sensitization to methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) has been reported previously (, ). Here, we describe 10 patients, 7 from Belgium and 3 from France, suffering from photoaggravated dermatitis, in some cases followed by transient photosensitivity, after sensitization to these biocides.Patients and MethodsTen patients, 5 men and 5 women, with a median age of 49.5 years, were investigated in Bordeaux, Marseille, and Toulouse (1 patient each; patients 1–3), in Antwerp (n = 4; patients 4–6 and patient 10) and in Leuven (n = 3; patients 7–9) between January 2012 and February 2017. All had presented with skin lesions in a photodistributed pattern, or showed more pronounced lesions on ultraviolet (UV)‐exposed skin regions, often involving the face and/or the back of the hands. Seven of them, upon referral to the patch test clinic, gave a clear history of consistent photoaggravation whenever their dermatitis was exposed to sunlight. In others (e.g. patient 2) the relative photodistribution of the skin lesions became apparent only during further follow‐up, when UV‐exposed skin became more prominently affected. For patients 7 and 9, no information had been documented regarding subjective symptoms upon sun exposure. However, also in these 2 patients, UV‐exposed skin areas were more strongly affected. Occasionally (patients

Journal

Contact DermatitisWiley

Published: Jan 1, 2018

Keywords: ; ; ; ; ; ; ; ; ; ;

References

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