Peripheral arterial stiffness as a surrogate of central hemodynamics: A new era for cardiovascular risk estimation?

Peripheral arterial stiffness as a surrogate of central hemodynamics: A new era for... He who cures a disease may be the skill fullest, but he that prevents it is the safest physician. —Thomas Fuller 1608‐1661, English Clergyman and Historian.This comment, made by one of the most emblematic personalities of the 17th century, highlights the widely accepted opinion of preventing, rather than curing, a disease. Prevention of cardiovascular (CV) disease, the leading cause of death worldwide, remains a challenging aspect in clinical practice and requires the timely recognition of patients at risk for CV events. Arterial hypertension, diabetes mellitus, dyslipidemia, and obesity, along with other traditional risk factors, have been identified as strong and independent predictors of CV disease; however, even these established risk factors fail to fully predict CV events. Research efforts have been emphasizing in unveiling novel CV risk factors that alone, or in combination, could offer a better stratification of CV risk. For a marker to be established as a valid risk factor, strong data indicating an independent association between the marker and CV morbidity and mortality, along with evidence supporting the marker's ability to predict CV events beyond traditional risk factors, is needed. More importantly, the management of emerging risk factors should offer reduction in CV outcomes.Arterial stiffness is http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Clinical Hypertension Wiley

Peripheral arterial stiffness as a surrogate of central hemodynamics: A new era for cardiovascular risk estimation?

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
Copyright © 2018 Wiley Periodicals, Inc.
ISSN
1524-6175
eISSN
1751-7176
D.O.I.
10.1111/jch.13204
Publisher site
See Article on Publisher Site

Abstract

He who cures a disease may be the skill fullest, but he that prevents it is the safest physician. —Thomas Fuller 1608‐1661, English Clergyman and Historian.This comment, made by one of the most emblematic personalities of the 17th century, highlights the widely accepted opinion of preventing, rather than curing, a disease. Prevention of cardiovascular (CV) disease, the leading cause of death worldwide, remains a challenging aspect in clinical practice and requires the timely recognition of patients at risk for CV events. Arterial hypertension, diabetes mellitus, dyslipidemia, and obesity, along with other traditional risk factors, have been identified as strong and independent predictors of CV disease; however, even these established risk factors fail to fully predict CV events. Research efforts have been emphasizing in unveiling novel CV risk factors that alone, or in combination, could offer a better stratification of CV risk. For a marker to be established as a valid risk factor, strong data indicating an independent association between the marker and CV morbidity and mortality, along with evidence supporting the marker's ability to predict CV events beyond traditional risk factors, is needed. More importantly, the management of emerging risk factors should offer reduction in CV outcomes.Arterial stiffness is

Journal

Journal of Clinical HypertensionWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

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