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Perforated demineralized bone matrix: A new form of osteoinductive biomaterial

Perforated demineralized bone matrix: A new form of osteoinductive biomaterial This study was undertaken to evaluate a new osteoinductive material—perforated decalcified bone matrix (PDBM). Subcutaneous implantation of PDBM induces multiple centers of endochondral osteogenesis with subsequent resorption of bone matrix and its replacement by new bone. PDBM should therefore prove useful as a research model to study osteoinduction and in the clinical situation in orthopedic and reconstructive surgery for the filling of bone defects and stimulation of fracture healing. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Biomedical Materials Research Part A Wiley

Perforated demineralized bone matrix: A new form of osteoinductive biomaterial

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References (9)

Publisher
Wiley
Copyright
Copyright © 1986 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1549-3296
eISSN
1552-4965
DOI
10.1002/jbm.820200603
pmid
3522592
Publisher site
See Article on Publisher Site

Abstract

This study was undertaken to evaluate a new osteoinductive material—perforated decalcified bone matrix (PDBM). Subcutaneous implantation of PDBM induces multiple centers of endochondral osteogenesis with subsequent resorption of bone matrix and its replacement by new bone. PDBM should therefore prove useful as a research model to study osteoinduction and in the clinical situation in orthopedic and reconstructive surgery for the filling of bone defects and stimulation of fracture healing.

Journal

Journal of Biomedical Materials Research Part AWiley

Published: Jul 1, 1986

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