Patch tests with fragrance materials and preservatives

Patch tests with fragrance materials and preservatives 179 patients suspected of cosmetic allergy were patch tested with a series of 16 fragrance materials and 9 preservatives. In 67 patients (37.4%), for more of these substances gave positive reactions. In the group of fragrance materials, the largest numbers of positive patch test reactions were seen to isocugenol, oak moss, geraniol, α‐amylcinnamic alcohol, and a mixture of α‐amylcinnamic aldehyde and α‐hexylcinnamic aldehyde. The fragrance mix in the ICDRG standard series detected nearly 80% of cases of contact allergy to fragrance materials other than its constituents. In the group of preservatives, Kathon CG® and quaternium‐15 scored the highest number of positive reactions. Its is argued that the commonly used patch test concentrate on of 2% for oak moss and geraniol may be too low to detect all cases of sensitization. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Contact Dermatitis Wiley

Patch tests with fragrance materials and preservatives

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Publisher
Wiley
Copyright
Copyright © 1985 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0105-1873
eISSN
1600-0536
DOI
10.1111/j.1600-0536.1985.tb01059.x
Publisher site
See Article on Publisher Site

Abstract

179 patients suspected of cosmetic allergy were patch tested with a series of 16 fragrance materials and 9 preservatives. In 67 patients (37.4%), for more of these substances gave positive reactions. In the group of fragrance materials, the largest numbers of positive patch test reactions were seen to isocugenol, oak moss, geraniol, α‐amylcinnamic alcohol, and a mixture of α‐amylcinnamic aldehyde and α‐hexylcinnamic aldehyde. The fragrance mix in the ICDRG standard series detected nearly 80% of cases of contact allergy to fragrance materials other than its constituents. In the group of preservatives, Kathon CG® and quaternium‐15 scored the highest number of positive reactions. Its is argued that the commonly used patch test concentrate on of 2% for oak moss and geraniol may be too low to detect all cases of sensitization.

Journal

Contact DermatitisWiley

Published: Feb 1, 1985

References

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