Neonatal skin barrier: structure, function, and disorders

Neonatal skin barrier: structure, function, and disorders ABSTRACT: The development of the human skin from intrauterine to extrauterine life is a balletic interplay of maturing layers and interlocking structures. We discuss this transition and then branch out to touch on issues of premature infant as well as neonatal skin care. Disruption of the barrier function due to toxins and development errors are expounded upon. Staph scalded skin syndrome, collodion membrane, bullous congenital ichthyosiform erythroderma, autosomal recessive ichthyosis (lamellar and congenital ichthyosiform erythroderma), and harlequin fetus are used as examples of these disruptions. Discussion of therapy with the authors’ experience highlights each disease. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Dermatologic Therapy Wiley

Neonatal skin barrier: structure, function, and disorders

Dermatologic Therapy, Volume 18 (2) – Mar 1, 2005

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Publisher
Wiley
Copyright
Copyright © 2005 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1396-0296
eISSN
1529-8019
D.O.I.
10.1111/j.1529-8019.2005.05011.x
Publisher site
See Article on Publisher Site

Abstract

ABSTRACT: The development of the human skin from intrauterine to extrauterine life is a balletic interplay of maturing layers and interlocking structures. We discuss this transition and then branch out to touch on issues of premature infant as well as neonatal skin care. Disruption of the barrier function due to toxins and development errors are expounded upon. Staph scalded skin syndrome, collodion membrane, bullous congenital ichthyosiform erythroderma, autosomal recessive ichthyosis (lamellar and congenital ichthyosiform erythroderma), and harlequin fetus are used as examples of these disruptions. Discussion of therapy with the authors’ experience highlights each disease.

Journal

Dermatologic TherapyWiley

Published: Mar 1, 2005

References

  • Topical ointment therapy benefits premature infants
    Nopper, Nopper; Horii, Horii; Sookdeo‐Drost, Sookdeo‐Drost; Wang, Wang; Mancini, Mancini; Lane, Lane

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