prine, one of the most widely used immunosuppressants, is gene expression and drug resistance, and gene amplification in eukaryotic cells. In the section on antiparasitic agents, the not discussed; neither are antibodies as drug delivery agents, drug-induced allergic reactions, xenobiotics in immunotoxi- topics include glycolysis as a target in the development of new trypanocidal agents, purine and pyrimidine metabolism cology, complex carbohydrates, or bacterial products used to in Trichomonadidae and Giardia, pyrazolopyrimidine me- enhance host defense against infectious disease. Whether tabolism in the pathogenic hemoflagellates, polyamine an- these are appropriate topics for inclusion depends upon your tagonists in the treatment of protozoan infection, the promo- definition of immunopharmacology. However, it is not tion and inhibition of the biosynthesis of cachectin, the action whether particular agents are included that should give the of praziquantel and the benzodiazepines on adult male Schis- reader pause, but the approach to the discussion of the tosoma mansoni, and serotonin receptors in trematodes. In agents. It is that of an immunologist writing about agents that affect the immune system; the principles of drug action the section on prostaglandins and leukotrienes, the topics include the formation, synthesis, and therapeutic potential of are secondary. Specific pharmacological topics,
Journal of Pharmaceutical Sciences – Wiley
Published: Aug 1, 1985
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