Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Bleecker, B. Paepe, I. Vanwalleghem, J. Schröder (2002)
Differential expression of chemokines in inflammatory myopathiesNeurology, 58
W. Brück, Phyllis Porada, S. Poser, P. Rieckmann, F. Hanefeld, Hans Kretzschmarch, H. Lassmann (1995)
Monocyte/macrophage differentiation in early multiple sclerosis lesionsAnnals of Neurology, 38
J. Bleecker, V. Meire, W. Declercq, E. Aken (1999)
Immunolocalization of tumor necrosis factor-alpha and its receptors in inflammatory myopathies 1 This paper was presented at the 50th Annual Meeting of the American Academy of Neurology, Minneapolis, MN, USA, April 1998. 1Neuromuscular Disorders, 9
P. Confalonieri, S. Galbiati, F. Cornelio, R. Mantegazza (2000)
Increased Expression of β‐Chemokines in Muscle of Patients with Inflammatory MyopathiesJNEN: Journal of Neuropathology & Experimental Neurology, 59
S. O'Laughlin, M. Braverman, M. Smith-Jefferies, P. Buckley (1992)
Macrophages (histiocytes) in various reactive and inflammatory conditions express different antigenic phenotypes.Human pathology, 23 12
M. Dalakas, K. Sivakumar (1996)
The immunopathologic and inflammatory differences between dermatomyositis, polymyositis and sporadic inclusion body myositisCurrent Opinion in Neurology, 9
G. Zwadlo, E. Bröcker, D. Bassewitz, U. Feige, C. Sorg (1985)
A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes.Journal of immunology, 134 3
K. Odink, N. Cerletti, J. Brüggen, R. Clerc, L. Tarcsay, G. Zwadlo, G. Gerhards, R. Schlegel, C. Sorg (1987)
Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritisNature, 330
Tina Yen, C. Harrison, J. Devery, S. Leong, S. Iismaa, T. Yoshimura, C. Geczy (1997)
Induction of the S100 chemotactic protein, CP-10, in murine microvascular endothelial cells by proinflammatory stimuli.Blood, 90 12
G. Zwadlo, R. Schlegel, C. Sorg (1986)
A monoclonal antibody to a subset of human monocytes found only in the peripheral blood and inflammatory tissues.Journal of immunology, 137 2
Reinhard Hohlfeld, Reinhard Hohlfeld, Andrew Engel, Norbert Goebels, Norbert Goebels, L. Behrens, L. Behrens (1997)
Cellular immune mechanisms in inflammatory myopathies.Current opinion in rheumatology, 9 6
R. Newton, N. Hogg (1998)
The human S100 protein MRP-14 is a novel activator of the beta 2 integrin Mac-1 on neutrophils.Journal of immunology, 160 3
P. Betz, J. Tübel, W. Eisenmenger (2005)
Immunohistochemical analysis of markers for different macrophage phenotypes and their use for a forensic wound age estimationInternational Journal of Legal Medicine, 107
W. Schulz-Schaeffer, W. Brück, K. Püschel (2005)
Macrophage subtyping in the determination of age of injection sitesInternational Journal of Legal Medicine, 109
C. Kerkhoff, I. Eue, C. Sorg (2000)
The Regulatory Role of MRP8 (S100A8) and MRP14 (S100A9) in the Transendothelial Migration of Human LeukocytesPathobiology, 67
R. Donato (1999)
Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type.Biochimica et biophysica acta, 1450 3
Kiefer Kiefer, Kieseier Kieseier, Brueck Brueck, Hartung Hartung, Toyka Toyka (1998)
Macrophage differentiation antigens in acute and chronic polyneuropathiesBrain, 121
G. Zwadlo, J. Brüggen, G. Gerhards, R. Schlegel, C. Sorg (1988)
Two calcium-binding proteins associated with specific stages of myeloid cell differentiation are expressed by subsets of macrophages in inflammatory tissues.Clinical and experimental immunology, 72 3
Reinhard Kiefer, B. Kieseier, Wolfgang Brück, H. Hartung, K. Toyka (1998)
Macrophage differentiation antigens in acute and chronic autoimmune polyneuropathies.Brain : a journal of neurology, 121 ( Pt 3)
(1994)
The polymyositis and dermatomyositis syndromes
Recent advances have revealed significant differences in the pathogenesis of inflammatory myopathies. To determine whether different patterns of macrophage differentiation are a useful tool to delineate the major groups of inflammatory myopathies, the muscle biopsies of 11 patients with dermatomyositis and 12 patients with polymyositis were studied using different macrophage markers. In polymyositis, the early‐activation markers MRP14 and 27E10 stained the majority of macrophages, which were recognized by the pan‐macrophage marker Ki‐M1P and which were located primarily in the endomysium. In dermatomyositis, macrophages predominantly expressed the late‐activation marker 25F9 and were found mainly in the perimysium. Thus, the location and presence of different subsets of macrophages distinguish dermatomyositis and polymyositis. The predominance of early‐activated macrophages in polymyositis indicates a more acute disease process. The findings in dermatomyositis, by contrast, suggest a role of persistent monocytes/macrophages in the disease process. Muscle Nerve 30: 225–230, 2004
Muscle and Nerve – Wiley
Published: Aug 1, 2004
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.