A simple and efficient synthesis of 2‐amino‐4‐aryl thiazole derivatives was carried out through the reaction of substituted acetophenones and thiourea using three different types of catalytic systems including N,N,N′,N′‐tetrabromobenzene‐1,3‐disulfonamide [TBBDA], poly(N,N′‐dibromo‐N‐ethylbenzene‐1,3‐disulfonamide) [PBBS] and a combination of TBBDA and nano‐magnetic catalyst supported with functionalized 4‐amino‐pyridine silica (MNPs@SiO2‐Pr‐AP). The results showed that the use of TBBDA along with the MNPs@SiO2‐Pr‐AP gains the highest yields of the products in the shortest reaction time.
Applied Organometallic Chemistry – Wiley
Published: Jan 1, 2018
Keywords: ; ; ; ;
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