Mineral features of connective dental hard tissues in hypoplastic amelogenesis imperfecta

Mineral features of connective dental hard tissues in hypoplastic amelogenesis imperfecta INTRODUCTIONAmelogenesis imperfecta (AI) is a heterogeneous group of hereditary disorders that may affect the enamel of teeth (Gadhia, McDonald, Arkutu, & Malik, ). This disorder is classified into four main groups, depending on the clinical presentation of the defects and the stage of enamel formation that is primarily affected (Aldred, Savarirayan, & Crawford, ). These groups are identified as (i) hypoplastic, (ii) hypocalcified/hypomineralized, (iii) hypomature, and (iv) hypomineralized/hypomature AI with taurodontism. For the hypoplastic type, pathological processes of mineralization, called calcinosis, are particularly described in the connective tissues of AI patients. Such calcinosis could be described in either kidneys, gingivae, or dental pulp (de la Dure‐Molla et al., ). The complex process by which precipitations of inorganic compounds within these organic matrices occur remains unclear. Besides, little is known about the structure and the mineralized compound of the dental hard tissues of mesenchymal origin such as dentin and cementum in the context of AI and particularly for the hypoplastic type.Dentin forms the largest portion of a tooth. It contains 70% carbonated apatite, 20% organic matrix mainly constituted by type I collagen, and 10% water by weight. The collagen matrix serves as a scaffold for crystal deposition, while the non‐collagenous proteins http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Oral Diseases Wiley

Mineral features of connective dental hard tissues in hypoplastic amelogenesis imperfecta

Loading next page...
 
/lp/wiley/mineral-features-of-connective-dental-hard-tissues-in-hypoplastic-oInn46FjcU
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
Copyright © 2018 John Wiley & Sons A/S. Published by John Wiley &Sons Ltd
ISSN
1354-523X
eISSN
1601-0825
D.O.I.
10.1111/odi.12724
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONAmelogenesis imperfecta (AI) is a heterogeneous group of hereditary disorders that may affect the enamel of teeth (Gadhia, McDonald, Arkutu, & Malik, ). This disorder is classified into four main groups, depending on the clinical presentation of the defects and the stage of enamel formation that is primarily affected (Aldred, Savarirayan, & Crawford, ). These groups are identified as (i) hypoplastic, (ii) hypocalcified/hypomineralized, (iii) hypomature, and (iv) hypomineralized/hypomature AI with taurodontism. For the hypoplastic type, pathological processes of mineralization, called calcinosis, are particularly described in the connective tissues of AI patients. Such calcinosis could be described in either kidneys, gingivae, or dental pulp (de la Dure‐Molla et al., ). The complex process by which precipitations of inorganic compounds within these organic matrices occur remains unclear. Besides, little is known about the structure and the mineralized compound of the dental hard tissues of mesenchymal origin such as dentin and cementum in the context of AI and particularly for the hypoplastic type.Dentin forms the largest portion of a tooth. It contains 70% carbonated apatite, 20% organic matrix mainly constituted by type I collagen, and 10% water by weight. The collagen matrix serves as a scaffold for crystal deposition, while the non‐collagenous proteins

Journal

Oral DiseasesWiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off