Alfred Guido Miescher was a professor of Dermatology at the University Hospital of Zurich and was passionate about dermatopathology. His landmark work, Histologie de 100 cas de naevi pigmentaires d'après les methods de Masson, published in 1935, included 100 hemispherical melanocytic nevi found mostly on women's faces and nowadays known as “Miescher's nevi.” Ten years later, he described cheilitis granulomatosa, subsequently also called Miescher cheilitis, one of the components of Melkersson‐Rosenthal syndrome.Miescher nevus is a dome‐shaped papule, usually located on women's faces and histologically characterized by melanocytes distributed endophytically, often in a wedge pattern.Nevertheless, apart from dermatologists, this nevus has been popularly referred to in two different ways: in fact, according to its position on the face, it can be a “devil's mark” or a “beauty mark.”If Miescher nevus was located on the nose or on the chin of a lady, it was considered, especially in the past, during the witchcraft trials, as a “devil's mark” or a “witch's mark.” Witch hunters believed that the devil imprinted on his human initiates clearly visible marks, usually described as dome‐shaped lesions with a wart‐like appearance on the face or as skin tags, or as supernumerary nipples. Practicing black magic was once
International Journal of Dermatology – Wiley
Published: Jan 1, 2018
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