Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Mechanisms and consequences of persistence of intracellular pathogens: leishmaniasis as an example

Mechanisms and consequences of persistence of intracellular pathogens: leishmaniasis as an example Summary Lifelong persistence after clinical cure of the primary infection is a characteristic feature of many intracellular pathogens, including viruses, bacteria and protozoa. The underlying mechanisms are complex and range from the passive protection against toxic effector molecules of the host and the remodelling of intracellular compartments as safe niches to the active modulation of the immune response at multiple levels. Parasites of the genus Leishmania have been particular helpful in unravelling some of the basic processes and form therefore the centre of the discussion. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cellular Microbiology Wiley

Mechanisms and consequences of persistence of intracellular pathogens: leishmaniasis as an example

Cellular Microbiology , Volume 10 (6) – Jun 1, 2008

Loading next page...
 
/lp/wiley/mechanisms-and-consequences-of-persistence-of-intracellular-pathogens-7ymwUHB3hD
Publisher
Wiley
Copyright
© 2008 The Author. Journal compilation © 2008 Blackwell Publishing Ltd
ISSN
1462-5814
eISSN
1462-5822
DOI
10.1111/j.1462-5822.2008.01146.x
pmid
18363880
Publisher site
See Article on Publisher Site

Abstract

Summary Lifelong persistence after clinical cure of the primary infection is a characteristic feature of many intracellular pathogens, including viruses, bacteria and protozoa. The underlying mechanisms are complex and range from the passive protection against toxic effector molecules of the host and the remodelling of intracellular compartments as safe niches to the active modulation of the immune response at multiple levels. Parasites of the genus Leishmania have been particular helpful in unravelling some of the basic processes and form therefore the centre of the discussion.

Journal

Cellular MicrobiologyWiley

Published: Jun 1, 2008

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$499/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month