Major vascular resections in retroperitoneal sarcoma

Major vascular resections in retroperitoneal sarcoma INTRODUCTIONSurgical resection is the cornerstone for the treatment of retroperitoneal soft tissue sarcoma (RPS), and it has the aim of minimizing marginality. Indeed, the local treatment is of utmost importance in the absence of validated systemic therapies in adjuvant setting. Moreover, we await the final results of STRASS, a randomized study evaluating the benefit of preoperative radiotherapy. Recently, a radical surgical approach involving en bloc resection of the tumor with adherent organs or structures has been advocated for optimizing survival and has led to a significant drop in the local recurrence rates compared to the historical recurrence rates. This radical surgical approach is safe when it is carried out at a specialist sarcoma center, but the decision regarding whether to resect an organ must be made by an experienced surgeon when considering histological subtype and morbidity. In particular, major vessel resections significantly increase the occurrence of post‐operative complications. In the retroperitoneal space, vascular sarcomas originating from the walls of the vessels co‐exist with retroperitoneal soft tissue sarcomas with secondary vascular involvement. In the latter, the retroperitoneal location and often the evolved size lead to the frequent involvement of the major vascular structures and may become a limitation for complete http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Surgical Oncology Wiley

Major vascular resections in retroperitoneal sarcoma

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
0022-4790
eISSN
1096-9098
D.O.I.
10.1002/jso.24920
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONSurgical resection is the cornerstone for the treatment of retroperitoneal soft tissue sarcoma (RPS), and it has the aim of minimizing marginality. Indeed, the local treatment is of utmost importance in the absence of validated systemic therapies in adjuvant setting. Moreover, we await the final results of STRASS, a randomized study evaluating the benefit of preoperative radiotherapy. Recently, a radical surgical approach involving en bloc resection of the tumor with adherent organs or structures has been advocated for optimizing survival and has led to a significant drop in the local recurrence rates compared to the historical recurrence rates. This radical surgical approach is safe when it is carried out at a specialist sarcoma center, but the decision regarding whether to resect an organ must be made by an experienced surgeon when considering histological subtype and morbidity. In particular, major vessel resections significantly increase the occurrence of post‐operative complications. In the retroperitoneal space, vascular sarcomas originating from the walls of the vessels co‐exist with retroperitoneal soft tissue sarcomas with secondary vascular involvement. In the latter, the retroperitoneal location and often the evolved size lead to the frequent involvement of the major vascular structures and may become a limitation for complete

Journal

Journal of Surgical OncologyWiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

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