Lupus erythematosus tumidus (LET) is a rare subtype of cutaneous lupus erythematosus. It usually occurs on sun‐exposed areas of skin and is characterized by erythematous, urticarial‐like, non‐scarring plaque and papules with a tendency to produce annular formations. Most LET patients are negative for antinuclear antibodies (ANA), and the association with systemic lupus erythematosus (SLE) is extremely rare. Although predominant in adults, some pediatric cases have been reported.A 12‐year‐old girl presented with a 5 day history of symptoms, consisting of non‐pruritic skin lesions on the face and upper chest accompanied by daily and high‐grade fever. She had no relevant medical or family history. Physical examination indicated a well‐appearing girl, with a remarkable rash on the face and upper chest and back characterized by erythematous, edematous and confluent papules and plaques that disappeared with pressure (Fig. a,b).(a,b) Skin lesions on admission to hospital: erythematous plaques and papules with a tendency to produce annular formations in sun‐exposed areas of skin. (c) Histopathology of the skin punch biopsy: perivascular and peri‐adnexal lymphocytic infiltrate and mucin deposition.Laboratory analysis indicated leukopenia (1,920/μL), and neutropenia (600/μL) confirmed on peripheral blood smear; normocytic anemia (11 g/dL), and normal platelet count (165 000/μL). Coagulation and all routine serum chemistries were normal, except
Pediatrics International – Wiley
Published: Jan 1, 2018
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