Low temperature plasma induced apoptosis in CNE‐2Z cells through endoplasmic reticulum stress and mitochondrial dysfunction pathways

Low temperature plasma induced apoptosis in CNE‐2Z cells through endoplasmic reticulum stress... INTRODUCTIONIn recent years, low temperature plasma (LTP) has attracted considerable attention, due to its ability of launching controllable plasma plumes in atmospheric pressure air, not confined by electrodes, dry procedure, high reactive efficiency, no hazardous residual, friendly to temperature sensitive material, and easy operation. The advantages of LTP are that large and expensive vacuum equipment can be omitted and high reactive species density can be achieved due to the high density under ambient conditions without significant thermal damage. The effect of LTP on the organism is comprehensive under the effects of various kinds of free radicals, the charged particles, ultraviolet, and excited states of particles on the organism. The composition and content of active components in the LTP can be controlled by adjusting the discharge parameters and the dose of plasma. Among these active components, reactive oxygen species (ROS) and reactive nitrogen species (RNS) such as NO, NO2, O3, OH, H2O2, are reported to contribute to LTP‐induced cell death and other effects. Therefore, LTP has gradually been used in biomedical applications, such as sterilization, dermopathic therapies, cancer therapies, wound healing therapies, and therapies involving the stomatology.Nasopharyngeal carcinoma (NPC) is a poorly differentiated carcinoma that arose from the epithelium of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Plasma Processes and Polymers Wiley

Low temperature plasma induced apoptosis in CNE‐2Z cells through endoplasmic reticulum stress and mitochondrial dysfunction pathways

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN
1612-8850
eISSN
1612-8869
D.O.I.
10.1002/ppap.201600249
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONIn recent years, low temperature plasma (LTP) has attracted considerable attention, due to its ability of launching controllable plasma plumes in atmospheric pressure air, not confined by electrodes, dry procedure, high reactive efficiency, no hazardous residual, friendly to temperature sensitive material, and easy operation. The advantages of LTP are that large and expensive vacuum equipment can be omitted and high reactive species density can be achieved due to the high density under ambient conditions without significant thermal damage. The effect of LTP on the organism is comprehensive under the effects of various kinds of free radicals, the charged particles, ultraviolet, and excited states of particles on the organism. The composition and content of active components in the LTP can be controlled by adjusting the discharge parameters and the dose of plasma. Among these active components, reactive oxygen species (ROS) and reactive nitrogen species (RNS) such as NO, NO2, O3, OH, H2O2, are reported to contribute to LTP‐induced cell death and other effects. Therefore, LTP has gradually been used in biomedical applications, such as sterilization, dermopathic therapies, cancer therapies, wound healing therapies, and therapies involving the stomatology.Nasopharyngeal carcinoma (NPC) is a poorly differentiated carcinoma that arose from the epithelium of

Journal

Plasma Processes and PolymersWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

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