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Journal of Surgical Oncology
Table of Contents
Volume 117, Number 1, January 1, 2018
Seminar: Retroperitoneal Sarcoma Surgery
Guest Editors: William W. Tseng, Raphael E. Pollock,
and Alessandro Gronchi
Retroperitoneal Sarcomas: Big Tumors That Involve More Than Just “Getting it Out”
William W. Tseng, Raphael E. Pollock, and Alessandro Gronchi
Historical Perspectives and Future Directions in the Surgical Management of Retroperitoneal Sarcoma
William W. Tseng, Hyun Jae Seo, Raphael E. Pollock, and Alessandro Gronchi
Retroperitoneal sarcomas (RPS) have fascinated and intrigued physicians both past and present. In this article,
we review the history and evolution of RPS surgery and conclude with future directions in the management
of this unique disease.
Pathology of Retroperitoneal Sarcomas: A Brief Review
Salvatore L. Renne and O. Hans Iwenofu
The inherent heterogenous nature of sarcomas is reﬂ ective of the signiﬁ cant morphologic overlap seen among
the different types. This often poses diagnostic challenges and mishaps especially for the generalist. In this review,
we highlight pertinent pathologic and molecular aspects of sarcomas, common in the retroperitoneum and relevant
to the surgical oncologist.
Imaging in Retroperitoneal Soft Tissue Sarcoma
Christina Messiou and Carlo Morosi
This review guides clinicians and radiologists through the use of imaging for the differential diagnosis of
retroperitoneal masses arising outside the solid abdominal viscera. Imaging appearances of the most
common retroperitoneal sarcoma subtypes are described. Assessing response to treatment, surveillance
and new advances in imaging are also discussed.
Current Principles of Surgery for Retroperitoneal Sarcomas
Mark Fairweather, Ricardo J. Gonzalez, Dirk Strauss, and Chandrajit P. Raut
Surgery is the only potentially curative treatment for patients with retroperitoneal sarcomas (RPS).
While the optimal approach to surgery for RPS continues to be debated, anatomic considerations and
tumor biology as deﬁ ned by the histologic subtype are critical components in guiding the extent of resection.
Major Vascular Resections in Retroperitoneal Sarcoma
Dimitri Tzanis, Touﬁ k Bouhadiba, Elodie Gaignard, and Sylvie Bonvalot
Retroperitoneal sarcomas frequently involve major vessels, which either originate from them or
secondarily encase or invade them. This paper aims to provide descriptions of the surgical strategy
and outcomes when major vessels are affected.
Soft Tissue Tumors of the Pelvis: Technical and Histological Considerations
John T. Mullen and Winan van Houdt
Soft tissue tumors of the pelvis present unique challenges given the narrow anatomic conﬁ nes of the bony
pelvis, the often locally aggressive nature of these tumors, as well as the major functional deﬁ cits that may
result from their resection. As such, patients with soft tissue tumors of the pelvis may be best served by referral
to high-volume centers with experience in the multidisciplinary treatment of these tumors utilizing a highly
individualized, histology-based treatment strategy.
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