Insulin and glucose response following oral glucose administration in well‐conditioned ponies

Insulin and glucose response following oral glucose administration in well‐conditioned ponies Summary Twenty‐three well‐conditioned ponies were evaluated for insulin and glucose response following oral glucose administration (1 g/kg bodyweight (bwt) as a 20 per cent solution). Ponies were defined as normal if total insulin secretion (TIS) was less than 149 μiu/ml h and the glucose concentration was below 11.1 ± 0.11 mmol/litre (200 ± 2 mg/dl) at all times following oral glucose administration. When glucose concentrations were maintained below 11.1 ± 0.11 mmol/litre, the area under the glucose curve (TG) was less than 17.4 mmol/litre/h (314 mg/dl/h). The ponies were assigned to four groups based on insulin and glucose response: Group 1 (n=7), normal; Group 2 (n=5), high insulin, normal glucose; Group 3 (n=8), high insulin, high glucose and Group 4 (n=3), high glucose, normal insulin. This classification is an initial attempt to define normal insulin and glucose response in ponies. Additional data need to be accumulated to define further insulin resistance and diabetes in ponies. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Equine Veterinary Journal Wiley

Insulin and glucose response following oral glucose administration in well‐conditioned ponies

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/lp/wiley/insulin-and-glucose-response-following-oral-glucose-administration-in-rylatzM04Z
Publisher
Wiley
Copyright
© 1992 EVJ Ltd
ISSN
0425-1644
eISSN
2042-3306
D.O.I.
10.1111/j.2042-3306.1992.tb04764.x
Publisher site
See Article on Publisher Site

Abstract

Summary Twenty‐three well‐conditioned ponies were evaluated for insulin and glucose response following oral glucose administration (1 g/kg bodyweight (bwt) as a 20 per cent solution). Ponies were defined as normal if total insulin secretion (TIS) was less than 149 μiu/ml h and the glucose concentration was below 11.1 ± 0.11 mmol/litre (200 ± 2 mg/dl) at all times following oral glucose administration. When glucose concentrations were maintained below 11.1 ± 0.11 mmol/litre, the area under the glucose curve (TG) was less than 17.4 mmol/litre/h (314 mg/dl/h). The ponies were assigned to four groups based on insulin and glucose response: Group 1 (n=7), normal; Group 2 (n=5), high insulin, normal glucose; Group 3 (n=8), high insulin, high glucose and Group 4 (n=3), high glucose, normal insulin. This classification is an initial attempt to define normal insulin and glucose response in ponies. Additional data need to be accumulated to define further insulin resistance and diabetes in ponies.

Journal

Equine Veterinary JournalWiley

Published: Feb 1, 1992

References

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