IntroductionIndolent T‐lymphoblastic proliferation (iT‐LBP) is a relatively recently recognised non‐neoplastic condition presenting with expansion of extrathymic T lymphoblasts. The T lymphoblasts are double‐positive for CD4 and CD8, and the condition requires careful discrimination from T‐lymphoblastic lymphoma (T‐LBL). Since Velankar et al. reported the first case of iT‐LBP in 1999, reports of iT‐LBP have been increasing, especially in recent years, and it is likely that the entity is not as rare as originally perceived. We report a case of acinic cell carcinoma (ACC) accompanied by iT‐LBP along with a brief summary of all 14 cases of iT‐LBP reported to date.Case reportA 51‐year‐old man noticed a left parotid tumour in January 2014, and came to our hospital in January 2015 because of gradual tumour enlargement. The white blood cell count, haemoglobin level, platelet count, white blood cell differential count, lactate dehydrogenase level and soluble interleukin‐2 receptor level were normal. Tumour resection was carried out in July 2015, and ACC was diagnosed. A dense infiltration of small to medium‐sized lymphocytes with blastic nuclear features accompanied by no atypia surrounded the ACC lesion, and immunohistochemistry showed these blastic cells to be positive for CD3 and terminal deoxynucleotidyl transferase (TdT) (Figure ) and negative
Histopathology – Wiley
Published: Jan 1, 2018
Keywords: ; ; ;
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