Identification, classification and anatomical segregation of cells with X‐like and Y‐like properties in the lateral geniculate nucleus of old‐world primates.

Identification, classification and anatomical segregation of cells with X‐like and Y‐like... 1. All the cells (158) that we studied in the lateral geniculate nuclei of Macaca nemestrina and Macaca irus could be distinguished as either X‐like or Y‐like on the basis of their responses to tests developed to classify cat retinal and lateral geniculate nucleus cells. These tests include responses to stationary spots, fast moving wands and moving gratings. 2. Response latencies to electrical stimulation of the optic chiasm were determined for 130 cells; no X‐like cell showed a latency shorter than 1‐7 ms, no Y‐like cell showed a latency longer than 1‐6 ms. Primate lateral geniculate nucleus cells with X‐like properties thus receive their excitatory input from retinal cells with slowly conducting axons and these most probably include the tonic ganglion cells described by Gouras (1968, 1969); Y‐like lateral geniculate nucleus cells are driven by retinal cells with faster conducting axons, most probably including the phasic ganglion cells described by Gouras. 3. Wiesel & Hubel (1966) classified monkey lateral geniculate nucleus cells into four main types based on their receptive‐field properties, as revealed by spectrally and spatially distinct stimuli. We find that all Type I and Type II cells show X‐like properties; all type IV cells show Y‐like properties. Type III consists of a subtype that show X‐like properties, here termed Type IIIx, and a subtype that show Y‐like properties, here termed Type IIIy. 4. The first cells encountered as the micro‐electrode reached the lateral geniculate nucleus were always X‐like. In some penetrations only X‐like cells were encountered as the electrode moved downward through the lateral geniculate nucleus. In the remaining penetrations, after recording X‐like cells through most of the lateral geniculate nucleus, Y‐like cells were then encountered. No X‐like cells were found below Y‐like cells. thus these two classes of cells are anatomically segregated within the primate lateral geniculate nucleus. Electrode marking showed the borger between X‐like and Y‐like cells to correspond to the border between the paro‐ and magnocellular layers of the lateral geniculate nucleus. Thus X‐like cells (i.e. Types I, II and IIIx) occur in the parvocellular layers, Y‐like cells (i.e. Types IIIy and IV)in the magnocellular layers. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Physiology Wiley

Identification, classification and anatomical segregation of cells with X‐like and Y‐like properties in the lateral geniculate nucleus of old‐world primates.

The Journal of Physiology, Volume 258 (2) – Jun 1, 1976

Loading next page...
 
/lp/wiley/identification-classification-and-anatomical-segregation-of-cells-with-tQvHdg9WL2
Publisher
Wiley
Copyright
© 2014 The Physiological Society
ISSN
0022-3751
eISSN
1469-7793
D.O.I.
10.1113/jphysiol.1976.sp011429
Publisher site
See Article on Publisher Site

Abstract

1. All the cells (158) that we studied in the lateral geniculate nuclei of Macaca nemestrina and Macaca irus could be distinguished as either X‐like or Y‐like on the basis of their responses to tests developed to classify cat retinal and lateral geniculate nucleus cells. These tests include responses to stationary spots, fast moving wands and moving gratings. 2. Response latencies to electrical stimulation of the optic chiasm were determined for 130 cells; no X‐like cell showed a latency shorter than 1‐7 ms, no Y‐like cell showed a latency longer than 1‐6 ms. Primate lateral geniculate nucleus cells with X‐like properties thus receive their excitatory input from retinal cells with slowly conducting axons and these most probably include the tonic ganglion cells described by Gouras (1968, 1969); Y‐like lateral geniculate nucleus cells are driven by retinal cells with faster conducting axons, most probably including the phasic ganglion cells described by Gouras. 3. Wiesel & Hubel (1966) classified monkey lateral geniculate nucleus cells into four main types based on their receptive‐field properties, as revealed by spectrally and spatially distinct stimuli. We find that all Type I and Type II cells show X‐like properties; all type IV cells show Y‐like properties. Type III consists of a subtype that show X‐like properties, here termed Type IIIx, and a subtype that show Y‐like properties, here termed Type IIIy. 4. The first cells encountered as the micro‐electrode reached the lateral geniculate nucleus were always X‐like. In some penetrations only X‐like cells were encountered as the electrode moved downward through the lateral geniculate nucleus. In the remaining penetrations, after recording X‐like cells through most of the lateral geniculate nucleus, Y‐like cells were then encountered. No X‐like cells were found below Y‐like cells. thus these two classes of cells are anatomically segregated within the primate lateral geniculate nucleus. Electrode marking showed the borger between X‐like and Y‐like cells to correspond to the border between the paro‐ and magnocellular layers of the lateral geniculate nucleus. Thus X‐like cells (i.e. Types I, II and IIIx) occur in the parvocellular layers, Y‐like cells (i.e. Types IIIy and IV)in the magnocellular layers.

Journal

The Journal of PhysiologyWiley

Published: Jun 1, 1976

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off