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Arguments are presented in favor of capability of poly(A)‐tracts of cellular RNA to form double helices in vivo. It is suggested that formation of the double helix in the mRNA poly(A) tail provides the basis for such processes as polyadenylation termination, PAB I synthesis autoregulation, and stabilization of ARE‐containing mRNA by ELAV‐like proteins.
IUBMB Life – Wiley
Published: Dec 1, 1999
Keywords: Autoregulation Of Pab i Synthesis; Elav‐like Proteins; Initiation Of Translation; Polyadenylation Termination; Polya Forms; Polya Tail; Stabilization Of Are‐containing Mrna
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