The emergence of human papillomavirus (HPV) as a significant contributor to the development of oropharyngeal carcinoma has generated significant interest into patient populations exposed to the virus and subsequent development of oropharyngeal carcinoma. Due to the increased treatment sensitivity and improved survival compared to non‐HPV tumors, the natural progression to investigate the presence of HPV exposure in nonoropharyngeal sites is crucial in personalizing treatment regimens to these patient populations.Previous reports have found that HPV has a tropism toward lymphoepithelial‐rich sites in the tonsil and base of tongue; therefore, the nasopharynx is the most intriguing site outside the oropharynx to study the prognostic impact of HPV. Numerous single institution studies have reported on the presence of HPV in nasopharyngeal carcinoma (NPC). However, small patient cohorts (5‐125 patients) with wide range of HPV positivity (10%‐80%) make conclusions on such data difficult. The largest multi‐institution cohort of patients with NPC with HPV data available found 13 of 125 patients (10%) harboring evidence of HPV. The accompanying publication by Dr Verma and his colleagues attempts to overcome limitations in patient numbers by using the National Cancer Database (NCDB) to study the prognostic impact of HPV in NPC at a population level. Evaluation of
Head & Neck: Journal for the Sciences & Specialties of the Head and Neck – Wiley
Published: Jan 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera