Horton sees a speck: automated testing undone by a fragment

Horton sees a speck: automated testing undone by a fragment Accurately identifying a patient's blood type and any underlying antibodies is a crucial step in the transfusion process. Several US Food and Drug Administration–approved automated analyzers are available for performing pretransfusion tests.The Ortho Vision analyzer (Ortho Clinical Diagnostics) is designed to automate in vitro immunohematology testing of human blood utilizing ID‐MTS (Micro Typing Systems, Inc., an Ortho‐Clinical Diagnostics Company) gel card technology. The imaging system consists of processing software and a high‐resolution camera that captures images of both sides of the card in black and white and in color. Images are captured before starting the test as a quality check and after processing to obtain the results. External contaminants can adhere to the card throughout the analyzer during processing causing a false positive. All positive and indeterminate results are flagged by the analyzer for review. Manual examination of the color images can aid in the determination of true agglutination versus debris, as debris will be displayed as black or gray on the color image, and will not show on both sides of the reagent card (see figure).Automation has made it possible for transfusion medicine services to provide efficient and quality care. The frequency of false positives due to debris http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Transfusion Wiley

Horton sees a speck: automated testing undone by a fragment

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Publisher
Wiley
Copyright
© 2018 AABB
ISSN
0041-1132
eISSN
1537-2995
D.O.I.
10.1111/trf.14408
Publisher site
See Article on Publisher Site

Abstract

Accurately identifying a patient's blood type and any underlying antibodies is a crucial step in the transfusion process. Several US Food and Drug Administration–approved automated analyzers are available for performing pretransfusion tests.The Ortho Vision analyzer (Ortho Clinical Diagnostics) is designed to automate in vitro immunohematology testing of human blood utilizing ID‐MTS (Micro Typing Systems, Inc., an Ortho‐Clinical Diagnostics Company) gel card technology. The imaging system consists of processing software and a high‐resolution camera that captures images of both sides of the card in black and white and in color. Images are captured before starting the test as a quality check and after processing to obtain the results. External contaminants can adhere to the card throughout the analyzer during processing causing a false positive. All positive and indeterminate results are flagged by the analyzer for review. Manual examination of the color images can aid in the determination of true agglutination versus debris, as debris will be displayed as black or gray on the color image, and will not show on both sides of the reagent card (see figure).Automation has made it possible for transfusion medicine services to provide efficient and quality care. The frequency of false positives due to debris

Journal

TransfusionWiley

Published: Jan 1, 2018

References

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