Hepatitis B virus DNA in peripheral blood leukocytes: A brief review

Hepatitis B virus DNA in peripheral blood leukocytes: A brief review Despite being essentially hepatotropic, hepatitis B virus has frequently been detected in peripheral blood leukocytes. In most cases, viral DNA has been detected by hybridisation, though, occasionally, evidence of viral RNA and virus‐specific proteins has been reported. Though definitive evidence is lacking, it appears likely that the virus is able to replicate in at least a subfraction of these cells. The possible consequences with respect to the transmission and reactivation of virus infections are discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Medical Virology Wiley

Hepatitis B virus DNA in peripheral blood leukocytes: A brief review

Journal of Medical Virology, Volume 31 (1) – May 1, 1990

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Publisher
Wiley
Copyright
Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company
ISSN
0146-6615
eISSN
1096-9071
D.O.I.
10.1002/jmv.1890310107
Publisher site
See Article on Publisher Site

Abstract

Despite being essentially hepatotropic, hepatitis B virus has frequently been detected in peripheral blood leukocytes. In most cases, viral DNA has been detected by hybridisation, though, occasionally, evidence of viral RNA and virus‐specific proteins has been reported. Though definitive evidence is lacking, it appears likely that the virus is able to replicate in at least a subfraction of these cells. The possible consequences with respect to the transmission and reactivation of virus infections are discussed.

Journal

Journal of Medical VirologyWiley

Published: May 1, 1990

References

  • Leucocyte hepatitis B virus DNA in acute and chronic hepatitis B virus infection
    Davison, Davison; Alexander, Alexander; Anastassakos, Anastassakos; Fagan, Fagan; Williams, Williams
  • State of hepatitis B virus DNA in leucocytes of hepatitis B patients
    Gu, Gu; Chen, Chen; Jiang, Jiang; Zhang, Zhang; Wu, Wu; Jiang, Jiang; Jian, Jian
  • Detection of mononuclear cells expressing hepatitis B virus in peripheral blood from HBsAg positive and negative patients by in situ hybridisation
    Hadchouel, Hadchouel; Pasquinelli, Pasquinelli; Fournier, Fournier; Hugon, Hugon; Scotto, Scotto; Bernard, Bernard; Brechot, Brechot
  • Presence of HBV DNA in Spermatozoa: A possible vertical transmission of HBV via the germ line
    Hadchouel, Hadchouel; Scotto, Scotto; Huret, Huret; Molinie, Molinie; Villa, Villa; Degos, Degos; Brechot, Brechot
  • Hepatitis B virus infection of cord blood leukocytes
    Shen, Shen; Choo, Choo; Wu, Wu; Ng, Ng; Han, Han

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