Consultant Dermatologist, The West Kent General Hospital, Maidstone, Kent, and St, Bartholomew's Hospital, Rochester, Kent. AND C, D. CALNAN. Profe,ssor of Dermatology, The Institute of Dermatology, St. John's Hospital for Diseases of the Skin, Leicester Square, London, W,C.2. EVER since the work of Jaeger and Pelloni (1950) in Switzerland, which drew attention to the relationship between cement dermatitis and contact sensitivity to hexavalent chromate salts, there has been a great deal of discussion about the precise aetiological role which the delayed type of hypersensitivity reaction to the chromate ion plays in the pathogenesis of this dermatitis. Much of the European dermatological literature states that chromate allergy is a sine qua non for the diagnosis of cement dermatitis and is its direct cause. The usual view of dermatologists in the United States is fairly represented by the following statement from a paper by Denton, Keenan and Birmingham (1954). " Moistened cement undoubtedly exerts a primary irritant action on the skin ; however, the recent findings of positive patch tests to hexavalent chromium in cement users indicates that allergic chromate sensitivity may initiate and maintain cement dermatitis. Soluble hexavalent chromium is apparently present in all cements to a varying degree.
British Journal of Dermatology – Wiley
Published: Aug 1, 1962
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