IntroductionColorectal cancer is one of the most common cancers worldwide, especially in developed countries. Most cases of colorectal cancer develop via an adenoma to carcinoma sequence. Therefore, early detection and removal of colorectal adenomas during colonoscopy may potentially prevent colorectal cancer. For this purpose, the etiologies and risk factors of colorectal adenomas, such as male gender, older age, obesity, metabolic syndrome, glucose intolerance, and hyperlipidemia, have taken on broader significance. Similarly, gallbladder polyps share some risk factors, including metabolic syndrome, male gender, age, and obesity. Moreover, there is a common epitope found on the epithelium of gallbladder and that of colorectal mucosa. In addition, gallbladder stones also appear to be associated with age, obesity, blood glucose, and blood pressure, although they are more prevalent in women.Gallbladder polyps and gallbladder stones share some risk factors, such as age, obesity, and metabolic abnormalities, with colorectal polyps. However, little is known about the association of gallbladder polyps and gallbladder stones with colorectal polyps. Although two studies showed a positive association between gallbladder polyps and colorectal adenomas or adenocarcinoma, only one study revealed that gallbladder polyps were risk factors for colorectal adenomas. Yamaji et al. showed strong association between gallbladder stones and colorectal
Journal of Gastroenterology and Hepatology – Wiley
Published: Jan 1, 2018
Keywords: ; ; ;
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