Clinical findingsA 21‐year‐old female presented with asymptomatic verrucous lesions evolving during the last 4 years in an infraumbilical tattoo made 6 years ago. She had no relevant medical history.Clinical examination revealed multiple discrete flat‐topped skin‐colored papules (Fig. ). They were smooth and had a uniform dimension around 2 mm of diameter, diffusely distributed in the most pigmented areas of the abdominal tattoo (Fig. ). She had two more tattoos in different regions of the body, made in different times, without associated lesions.Multiple flat‐topped papules distributed in pigmented areas of the infraumbilical tattooDetailed view of the cutaneous lesions present in the tattooHistopathological and other findingsHistopathological examination revealed well‐defined proliferation of basaloid and squamoid epidermal cells (Fig. a). Black pigment was observed in macrophages lying preferentially in a perivascular location (Fig. b).Well‐defined proliferation of basaloid and squamoid epidermal cells (a) HE × 100; black pigment is observed in macrophages lying preferentially in a perivascular location (b) HE × 400Human papillomavirus (HPV) in the specimen revealed negative through polymerase chain reaction (PCR) assay.DiagnosisSeborrheic keratosis (SK).Clinical courseAfter confirming the diagnosis of SK, the patient started treatment with CO2 laser, and skin lesions revealed progressive improvement.DiscussionPrevious studies show that patients may be inoculated with HPV during tattoo procedures. There are only a few reports of
International Journal of Dermatology – Wiley
Published: Jan 1, 2018
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