Facile Fabrication of Mussel‐Inspired Multifunctional Polymeric Membranes with Remarkable Anticoagulant, Antifouling, and Antibacterial Properties

Facile Fabrication of Mussel‐Inspired Multifunctional Polymeric Membranes with Remarkable... Herein, a facile one‐step surface modification technique of coating functional biopolymer conjugated mussel‐inspired catechol (CA) onto substrate is applied to confer polyethersulfone (PES) membranes with remarkable blood compatibility, antifouling property, and antibacterial property, respectively. CA conjugated poly(2‐acrylamido‐2‐methylpropanesulfonic acid) (PAMPS), poly(sulfobetaine methacrylate) (PSBMA), and poly(methacryloxyethyltrimethyl ammonium chloride) are synthesized via free radical polymerization in the presence of CA, and simultaneously coated onto PES membrane surface. The surface chemical compositions, surface zeta‐potential convince the successful preparation of the modified PES membranes. PAMPS‐coated membrane exhibits excellent blood compatibility, especially anticoagulation property; PSBMA‐coated membrane displays excellent antifouling property and blood compatibility; meanwhile, PDMC‐coated membrane shows robust bactericidal property. In general, this work demonstrates that the mussel‐inspired surface modification protocol provides a facile and versitile method to confer the substrate with excellent blood compatibility, antifouling property, and antibacterial property, respectively, which has great potential for multibiomedical applications, such as blood purification, hemodialysis, and organ implantation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Macromolecular Materials & Engineering Wiley

Facile Fabrication of Mussel‐Inspired Multifunctional Polymeric Membranes with Remarkable Anticoagulant, Antifouling, and Antibacterial Properties

Loading next page...
 
/lp/wiley/facile-fabrication-of-mussel-inspired-multifunctional-polymeric-0EpIWT1mHT
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN
1438-7492
eISSN
1439-2054
D.O.I.
10.1002/mame.201700378
Publisher site
See Article on Publisher Site

Abstract

Herein, a facile one‐step surface modification technique of coating functional biopolymer conjugated mussel‐inspired catechol (CA) onto substrate is applied to confer polyethersulfone (PES) membranes with remarkable blood compatibility, antifouling property, and antibacterial property, respectively. CA conjugated poly(2‐acrylamido‐2‐methylpropanesulfonic acid) (PAMPS), poly(sulfobetaine methacrylate) (PSBMA), and poly(methacryloxyethyltrimethyl ammonium chloride) are synthesized via free radical polymerization in the presence of CA, and simultaneously coated onto PES membrane surface. The surface chemical compositions, surface zeta‐potential convince the successful preparation of the modified PES membranes. PAMPS‐coated membrane exhibits excellent blood compatibility, especially anticoagulation property; PSBMA‐coated membrane displays excellent antifouling property and blood compatibility; meanwhile, PDMC‐coated membrane shows robust bactericidal property. In general, this work demonstrates that the mussel‐inspired surface modification protocol provides a facile and versitile method to confer the substrate with excellent blood compatibility, antifouling property, and antibacterial property, respectively, which has great potential for multibiomedical applications, such as blood purification, hemodialysis, and organ implantation.

Journal

Macromolecular Materials & EngineeringWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial