Extranodal natural killer/T‐cell lymphoma, nasal type, in Senegal

Extranodal natural killer/T‐cell lymphoma, nasal type, in Senegal IntroductionExtranodal NK/T‐cell lymphoma (ENKTCL) is a rare entity, recently individualized in the new WHO classification and accounting for only 0.5% of Non‐Hodgkin's Lymphoma (NHL). It is characterized by its constant association with chronic EBV infection. The frequency of cutaneous involvement, as well as the poor prognosis of this lymphoma, justifies its importance and relevance to the dermatologist.The distribution of ENKTCL is very inhomogeneous throughout the world. Thus, this lymphoma is more frequent in Asian countries, in addition to Central and South America, where it represents 5–10% of the NHL. In the West, it is exceptional, with an incidence of less than 1% of all lymphomas. In Sub‐Saharan Africa (SSA), ENKTCL has been exceptionally reported despite the precocity and the endemicity of EBV infection.The purpose of this study was to report the epidemiological, clinical, paraclinical, and evolutionary characteristics of ENKTCL at the Aristide LeDantec University Hospital in Dakar, Senegal.Patients and methodsWe conducted a 5‐year retrospective study from 2011 to 2016 in the Department of Dermatology of the University Hospital of Dakar, Senegal. The medical records of all patients with histopathological, immunohistochemical, and in situ hybridization proven were reviewed.ResultsWe collected a total of seven cases, and this corresponded with a frequency http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Dermatology Wiley

Extranodal natural killer/T‐cell lymphoma, nasal type, in Senegal

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
International Journal of Dermatology © 2018 International Society of Dermatology
ISSN
0011-9059
eISSN
1365-4632
D.O.I.
10.1111/ijd.13921
Publisher site
See Article on Publisher Site

Abstract

IntroductionExtranodal NK/T‐cell lymphoma (ENKTCL) is a rare entity, recently individualized in the new WHO classification and accounting for only 0.5% of Non‐Hodgkin's Lymphoma (NHL). It is characterized by its constant association with chronic EBV infection. The frequency of cutaneous involvement, as well as the poor prognosis of this lymphoma, justifies its importance and relevance to the dermatologist.The distribution of ENKTCL is very inhomogeneous throughout the world. Thus, this lymphoma is more frequent in Asian countries, in addition to Central and South America, where it represents 5–10% of the NHL. In the West, it is exceptional, with an incidence of less than 1% of all lymphomas. In Sub‐Saharan Africa (SSA), ENKTCL has been exceptionally reported despite the precocity and the endemicity of EBV infection.The purpose of this study was to report the epidemiological, clinical, paraclinical, and evolutionary characteristics of ENKTCL at the Aristide LeDantec University Hospital in Dakar, Senegal.Patients and methodsWe conducted a 5‐year retrospective study from 2011 to 2016 in the Department of Dermatology of the University Hospital of Dakar, Senegal. The medical records of all patients with histopathological, immunohistochemical, and in situ hybridization proven were reviewed.ResultsWe collected a total of seven cases, and this corresponded with a frequency

Journal

International Journal of DermatologyWiley

Published: Jan 1, 2018

References

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