Exertional hypoxemia is more severe in fibrotic interstitial lung disease than in COPD

Exertional hypoxemia is more severe in fibrotic interstitial lung disease than in COPD Abbreviations6MWD6‐min walk distance6MWT6‐min walk testDLCOdiffusion capacity of the lung for carbon monoxideFEV1forced expiratory volume in 1 sFVCforced vital capacityILDinterstitial lung diseasePFTpulmonary function testRVresidual volumeSpO2oxygen saturationTLCtotal lung capacityINTRODUCTIONInterstitial lung disease (ILD) is a diverse group of entities that cause damage to the lung parenchyma through varying degrees of inflammation and fibrosis. Fibrotic ILDs result in restrictive ventilatory physiology and impaired gas exchange, frequently leading to exertional hypoxemia and functional limitation. The clinical and prognostic importance of exertional hypoxemia is well established, with multiple studies demonstrating a strong correlation of exertional desaturation with dyspnoea and mortality. Despite its importance, few studies have evaluated the severity, predictors and management of exertional oxygen desaturation in fibrotic ILD.Chronic obstructive pulmonary disease (COPD) is a common condition typically caused by cigarette smoking that results in a chronic inflammatory response involving the airways and lung parenchyma. COPD is characterized by persistent and progressive airflow limitation as well as impaired gas exchange that leads to dyspnoea and functional limitation. Despite similar features of dyspnoea and functional limitation in both ILD and COPD, the extent of exertional hypoxemia is often profound in patients with advanced ILD and may be more severe than in COPD. The objectives of this http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Respirology Wiley

Exertional hypoxemia is more severe in fibrotic interstitial lung disease than in COPD

Loading next page...
 
/lp/wiley/exertional-hypoxemia-is-more-severe-in-fibrotic-interstitial-lung-2CnigLvBO4
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Asian Pacific Society of Respirology
ISSN
1323-7799
eISSN
1440-1843
D.O.I.
10.1111/resp.13226
Publisher site
See Article on Publisher Site

Abstract

Abbreviations6MWD6‐min walk distance6MWT6‐min walk testDLCOdiffusion capacity of the lung for carbon monoxideFEV1forced expiratory volume in 1 sFVCforced vital capacityILDinterstitial lung diseasePFTpulmonary function testRVresidual volumeSpO2oxygen saturationTLCtotal lung capacityINTRODUCTIONInterstitial lung disease (ILD) is a diverse group of entities that cause damage to the lung parenchyma through varying degrees of inflammation and fibrosis. Fibrotic ILDs result in restrictive ventilatory physiology and impaired gas exchange, frequently leading to exertional hypoxemia and functional limitation. The clinical and prognostic importance of exertional hypoxemia is well established, with multiple studies demonstrating a strong correlation of exertional desaturation with dyspnoea and mortality. Despite its importance, few studies have evaluated the severity, predictors and management of exertional oxygen desaturation in fibrotic ILD.Chronic obstructive pulmonary disease (COPD) is a common condition typically caused by cigarette smoking that results in a chronic inflammatory response involving the airways and lung parenchyma. COPD is characterized by persistent and progressive airflow limitation as well as impaired gas exchange that leads to dyspnoea and functional limitation. Despite similar features of dyspnoea and functional limitation in both ILD and COPD, the extent of exertional hypoxemia is often profound in patients with advanced ILD and may be more severe than in COPD. The objectives of this

Journal

RespirologyWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off