IntroductionApproximately 40% of individuals with autism spectrum disorder (ASD) meet criteria for an anxiety disorder [van Steensel, Bögels, & Perrin, ], leading to increased distress and impairment [e.g., Kerns, Newschaffer, & Berkowitz, ]. Symptoms of generalized anxiety (GAD), obsessive‐compulsive (OCD), and social anxiety disorder (SAD), are often characteristic of anxiety in ASD [Hallett et al., ; Kerns, Kendall, Wood, & Storch, ]. In non‐ASD samples, these symptoms are associated with a larger error‐related negativity [ERN; e.g., Kujawa et al., ; Weinberg, Riesel, et al., ], an event‐related potential (ERP) in the scalp‐derived electroencephalogram (EEG) that is thought to reflect endogenous threat sensitivity [Weinberg, Klein, & Hajcak, ] or decreased cognitive control due to worry [Moser, Moran, Schroder, Donnellan, & Yeung, ]. Examining the relation of the ERN to anxiety symptoms can help clarify the role of threat sensitivity in the phenotypic profile of anxiety in ASD populations. However, results of extant research on the ERN and anxiety in ASD are highly variable [Hüpen, Groen, Gaastra, Tucha, & Tucha, ]. This may be due, in part, to a focus on broad measures of anxiety, rather than the specific symptoms likely to be associated with the ERN. In addition, factors known
Autism Research – Wiley
Published: Jan 1, 2018
Keywords: ; ; ; ;
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