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Epithelial corneal oedema treated with honey

Epithelial corneal oedema treated with honey Honey was used in the Bible and Talmud ‘as a remedy’ (Shabbath 77b‐78a) and to treat bulimia ‘so the eyes sparkle again’ (Baba Kamma 85a). The acidic hyperosmotic milieu and the presence of the enzyme inhibin confer unique antimicrobial properties to honey. Honey was mentioned in the Talmud as having a propitious effect on the eyes: ‘Honey enlightens the eyes of man’ (Yoma 83b). This prompted a prospective study of topical honey as a hyperosmotic agent in the therapy of epithelial corneal oedema. Prospectively, 16 consecutive patients with epithelial corneal oedema who were not surgical candidates and who attended a private clinic from January 2000 to June 2000 formed the study population. Honey was applied to the cornea after informed consent. The 16 patients were not candidates for any surgical intervention (systemic contraindication, uniocular, multiple ocular conditions, poor candidate for penetrating keratoplasty, unreliable for follow‐up or drug therapy, refusal for surgery). A drop of honey was applied using a sterile cotton applicator. The documentation of corneal clearing was performed over several visits (mean two visits). Patients were given the option of using topical honey outside the clinic, if tolerated, 4−5 times daily. All corneas had an immediate complete http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical & Experimental Ophthalmology Wiley

Epithelial corneal oedema treated with honey

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Publisher
Wiley
Copyright
Copyright © 2002 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1442-6404
eISSN
1442-9071
DOI
10.1046/j.1442-6404.2002.00482.x
Publisher site
See Article on Publisher Site

Abstract

Honey was used in the Bible and Talmud ‘as a remedy’ (Shabbath 77b‐78a) and to treat bulimia ‘so the eyes sparkle again’ (Baba Kamma 85a). The acidic hyperosmotic milieu and the presence of the enzyme inhibin confer unique antimicrobial properties to honey. Honey was mentioned in the Talmud as having a propitious effect on the eyes: ‘Honey enlightens the eyes of man’ (Yoma 83b). This prompted a prospective study of topical honey as a hyperosmotic agent in the therapy of epithelial corneal oedema. Prospectively, 16 consecutive patients with epithelial corneal oedema who were not surgical candidates and who attended a private clinic from January 2000 to June 2000 formed the study population. Honey was applied to the cornea after informed consent. The 16 patients were not candidates for any surgical intervention (systemic contraindication, uniocular, multiple ocular conditions, poor candidate for penetrating keratoplasty, unreliable for follow‐up or drug therapy, refusal for surgery). A drop of honey was applied using a sterile cotton applicator. The documentation of corneal clearing was performed over several visits (mean two visits). Patients were given the option of using topical honey outside the clinic, if tolerated, 4−5 times daily. All corneas had an immediate complete

Journal

Clinical & Experimental Ophthalmology – Wiley

Published: Feb 1, 2002

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