Endogenous Cannabinoids: Structure and Metabolism

Endogenous Cannabinoids: Structure and Metabolism The finding of specific binding sites for Δ9‐tetrahydrocannabinol, the psychoactive component of Cannabis sativa, has led to the discovery of the endocannabinoid system and has emphasised the physiological and pathological relevance of endocannabidoid lipid signalling. Subsequently, an increasing number of papers have been published on the biochemistry and pharmacology of endocannabinoids. An overview of the current understanding of structure and metabolism of the best studied endocannabinoids is provided, with a focus on the mechanisms responsible for their biosynthesis and inactivation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Neuroendocrinology Wiley

Endogenous Cannabinoids: Structure and Metabolism

Journal of Neuroendocrinology, Volume 20 – May 1, 2008

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Publisher
Wiley
Copyright
© 2008 Blackwell Publishing Ltd. No claim to original works
ISSN
0953-8194
eISSN
1365-2826
D.O.I.
10.1111/j.1365-2826.2008.01676.x
Publisher site
See Article on Publisher Site

Abstract

The finding of specific binding sites for Δ9‐tetrahydrocannabinol, the psychoactive component of Cannabis sativa, has led to the discovery of the endocannabinoid system and has emphasised the physiological and pathological relevance of endocannabidoid lipid signalling. Subsequently, an increasing number of papers have been published on the biochemistry and pharmacology of endocannabinoids. An overview of the current understanding of structure and metabolism of the best studied endocannabinoids is provided, with a focus on the mechanisms responsible for their biosynthesis and inactivation.

Journal

Journal of NeuroendocrinologyWiley

Published: May 1, 2008

References

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