Endocannabinoids in arthritis: current views and perspective

Endocannabinoids in arthritis: current views and perspective Preclinical and clinical studies using cannabis‐based therapy have been shown to provide both analgesia and anti‐inflammatory effects, with an overall alleviation of clinical symptoms in animal models of arthritis, highlighting its promising therapeutic application for humans. Despite this, the development of cannabis‐based therapeutics remains in its infancy, with further investigation into its efficacy and safety profile in patients still required. This synopsis reviews the various components of the endocannabinoid system in health and disease and their potential as therapeutic targets. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Rheumatic Diseases Wiley

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Publisher
Wiley
Copyright
International Journal of Rheumatic Diseases © 2017 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd
ISSN
1756-1841
eISSN
1756-185X
D.O.I.
10.1111/1756-185X.13146
Publisher site
See Article on Publisher Site

Abstract

Preclinical and clinical studies using cannabis‐based therapy have been shown to provide both analgesia and anti‐inflammatory effects, with an overall alleviation of clinical symptoms in animal models of arthritis, highlighting its promising therapeutic application for humans. Despite this, the development of cannabis‐based therapeutics remains in its infancy, with further investigation into its efficacy and safety profile in patients still required. This synopsis reviews the various components of the endocannabinoid system in health and disease and their potential as therapeutic targets.

Journal

International Journal of Rheumatic DiseasesWiley

Published: Jul 1, 2017

Keywords: ; ; ; ;

References

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