Efficacy Versus Systemic Effects of Six Topical Steroids in the Treatment of Atopic Dermatitis of Childhood

Efficacy Versus Systemic Effects of Six Topical Steroids in the Treatment of Atopic Dermatitis of... Abstract: Six groups of children suffering from widespread atopic dermatitis were treated once daily with six topical steroids of different potency. Systemic effects were measured by the morning estimation of plasma cortisol, A clear relationship was demonstrated between clinical efficacy of the steroid treatment and degree of reduced adrenal function. This study demonstrated that a rapid and marked therapeutic effect can be obtained with potent topical steroids applied once daily without occlusion, but in children is accompanied by a fall in plasma cortisol. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Dermatology Wiley

Efficacy Versus Systemic Effects of Six Topical Steroids in the Treatment of Atopic Dermatitis of Childhood

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Publisher
Wiley
Copyright
Copyright © 1984 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0736-8046
eISSN
1525-1470
DOI
10.1111/j.1525-1470.1984.tb01124.x
Publisher site
See Article on Publisher Site

Abstract

Abstract: Six groups of children suffering from widespread atopic dermatitis were treated once daily with six topical steroids of different potency. Systemic effects were measured by the morning estimation of plasma cortisol, A clear relationship was demonstrated between clinical efficacy of the steroid treatment and degree of reduced adrenal function. This study demonstrated that a rapid and marked therapeutic effect can be obtained with potent topical steroids applied once daily without occlusion, but in children is accompanied by a fall in plasma cortisol.

Journal

Pediatric DermatologyWiley

Published: Jan 1, 1984

References

  • Pituitary‐adrenal function after prolonged use of topical corticosteroids
    Munro, Munro; Clift, Clift

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