Access the full text.
Sign up today, get DeepDyve free for 14 days.
Yiping Li, Roberto Rey-Dios, D. Roberts, P. Valdes, A. Cohen-Gadol (2014)
Intraoperative fluorescence-guided resection of high-grade gliomas: a comparison of the present techniques and evolution of future strategies.World neurosurgery, 82 1-2
S. Harmsen, Ruimin Huang, M. Wall, Hazem Karabeber, Jason Samii, M. Spaliviero, Julie White, S. Monette, R. O'Connor, K. Pitter, Stephen Sastra, M. Saborowski, E. Holland, S. Singer, K. Olive, S. Lowe, R. Blasberg, M. Kircher (2015)
Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imagingScience Translational Medicine, 7
I. Stoffels, S. Morscher, I. Helfrich, U. Hillen, Julia Leyh, N. Burton, Thomas Sardella, J. Claussen, T. Poeppel, H. Bachmann, A. Roesch, K. Griewank, D. Schadendorf, M. Gunzer, J. Klode (2015)
Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imagingScience Translational Medicine, 7
A. Zerda, Sunil Bodapati, R. Teed, M. Schipper, S. Keren, B. Smith, Johnny Ng, S. Gambhir (2010)
A Comparison Between Time Domain and Spectral Imaging Systems for Imaging Quantum Dots in Small Living AnimalsMolecular Imaging and Biology, 12
M. Wall, S. Harmsen, Soumik Pal, L. Zhang, Gianluca Arianna, J. Lombardi, C. Drain, M. Kircher (2017)
Surfactant‐Free Shape Control of Gold Nanoparticles Enabled by Unified Theoretical Framework of Nanocrystal SynthesisAdvanced Materials, 29
C. Zavaleta, E. Garai, Jonathan Liu, S. Sensarn, M. Mandella, Dominique Sompel, S. Friedland, J. Dam, C. Contag, S. Gambhir (2013)
A Raman-based endoscopic strategy for multiplexed molecular imagingProceedings of the National Academy of Sciences, 110
Toms (2005)
10.1093/neurosurgery/57.2.382Neurosurgery, 57
A. Moiyadi, P. Shetty, E. Sridhar (2017)
Periventricular glioblastomas and ependymal involvement interrogated using intraoperative fluorescence – a pathological correlative studyBritish Journal of Neurosurgery, 31
S. Hervey-Jumper, M. Berger (2016)
Maximizing safe resection of low- and high-grade gliomaJournal of Neuro-Oncology, 130
W. Stummer, U. Pichlmeier, T. Meinel, O. Wiestler, F. Zanella, H. Reulen (2006)
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial.The Lancet. Oncology, 7 5
Evan Phillips, Oula Peñate-Medina, P. Zanzonico, R. Carvajal, Pauliah Mohan, Y. Ye, J. Humm, M. Gönen, H. Kalaigian, H. Schöder, H. Strauss, S. Larson, Ulrich Wiesner, M. Bradbury (2014)
Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probeScience Translational Medicine, 6
Ruimin Huang, S. Harmsen, Jason Samii, Hazem Karabeber, K. Pitter, E. Holland, M. Kircher (2016)
High Precision Imaging of Microscopic Spread of Glioblastoma with a Targeted Ultrasensitive SERRS Molecular Imaging ProbeTheranostics, 6
A. Rosenthal, D. Razansky, V. Ntziachristos (2010)
Fast Semi-Analytical Model-Based Acoustic Inversion for Quantitative Optoacoustic TomographyIEEE Transactions on Medical Imaging, 29
G. Diot, S. Metz, A. Noske, E. Liapis, Barbara Schroeder, S. Ovsepian, R. Meier, E. Rummeny, V. Ntziachristos (2017)
Multispectral Optoacoustic Tomography (MSOT) of Human Breast CancerClinical Cancer Research, 23
Lutz Lüdemann, Bernd Hamm, Claus Zimmer (2000)
Pharmacokinetic analysis of glioma compartments with dynamic Gd-DTPA-enhanced magnetic resonance imaging.Magnetic resonance imaging, 18 10
A. Thakor, R. Luong, R. Paulmurugan, Frank Lin, P. Kempen, C. Zavaleta, Pauline Chu, T. Massoud, R. Sinclair, S. Gambhir (2011)
The Fate and Toxicity of Raman-Active Silica-Gold Nanoparticles in MiceScience Translational Medicine, 3
D. Razansky, M. Distel, Claudio Vinegoni, Rui Ma, N. Perrimon, R. Köster, V. Ntziachristos (2009)
Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivoNature Photonics, 3
V. Neuschmelting, N. Burton, H. Lockau, Alexander Urich, S. Harmsen, V. Ntziachristos, M. Kircher (2015)
Performance of a Multispectral Optoacoustic Tomography (MSOT) System equipped with 2D vs. 3D Handheld Probes for Potential Clinical TranslationPhotoacoustics, 4
S. Harmsen, M. Bedics, M. Wall, Ruimin Huang, M. Detty, M. Kircher (2015)
Rational Design of a Chalcogenopyrylium-Based Surface-Enhanced Resonance Raman Scattering-Nanoprobe with Attomolar SensitivityNature communications, 6
N. Burton, Manishkumar Patel, S. Morscher, W. Driessen, J. Claussen, N. Beziere, Thomas Jetzfellner, A. Taruttis, D. Razansky, B. Bednar, V. Ntziachristos (2013)
Multispectral Opto-acoustic Tomography (MSOT) of the Brain and Glioblastoma CharacterizationNeuroImage, 65
G. Steiner, M. Kirsch (2013)
Optical spectroscopic methods for intraoperative diagnosisAnalytical and Bioanalytical Chemistry, 406
M. Jermyn, K. Mok, J. Mercier, J. Desroches, Julien Pichette, Karl Saint-Arnaud, Liane Bernstein, M. Guiot, K. Petrecca, F. Leblond (2015)
Intraoperative brain cancer detection with Raman spectroscopy in humansScience Translational Medicine, 7
Y. Li, D. Suki, K. Hess, R. Sawaya (2016)
The influence of maximum safe resection of glioblastoma on survival in 1229 patients: Can we do better than gross-total resection?Journal of neurosurgery, 124 4
A. Anselmo, S. Mitragotri (2015)
A Review of Clinical Translation of Inorganic NanoparticlesThe AAPS Journal, 17
M. Reinges, Hong-Ha Nguyen, T. Krings, B. Hütter, V. Rohde, J. Gilsbach (2004)
Course of brain shift during microsurgical resection of supratentorial cerebral lesions: limits of conventional neuronavigationActa Neurochirurgica, 146
V. Ntziachristos, Andreas Buehler (2017)
Multispectral optoacoustic tomographyScholarpedia, 12
B. Suchorska, M. Weller, G. Tabatabai, C. Senft, P. Hau, M. Sabel, U. Herrlinger, R. Ketter, U. Schlegel, C. Marosi, G. Reifenberger, W. Wick, J. Tonn, H. Wirsching (2015)
Complete resection of contrast-enhancing tumor volume is associated with improved survival in recurrent glioblastoma-results from the DIRECTOR trial.Neuro-oncology, 18 4
M. Kircher, A. Zerda, J. Jokerst, C. Zavaleta, P. Kempen, E. Mittra, K. Pitter, Ruimin Huang, Carl Campos, F. Habte, R. Sinclair, C. Brennan, I. Mellinghoff, E. Holland, S. Gambhir (2011)
A Brain Tumor Molecular Imaging Strategy Using A New Triple-Modality MRI-Photoacoustic-Raman NanoparticleNature medicine, 18
(2000)
A u th o r M a n u s c ip t A u th o r M a n u s c ip t A u th o r M a n u s c ip t A u th o r M a n u s c ip t
M. Eljamel, S. Mahboob (2016)
The effectiveness and cost-effectiveness of intraoperative imaging in high-grade glioma resection; a comparative review of intraoperative ALA, fluorescein, ultrasound and MRI.Photodiagnosis and photodynamic therapy, 16
V. Neuschmelting, H. Lockau, V. Ntziachristos, J. Grimm, M. Kircher (2016)
Lymph Node Micrometastases and In-Transit Metastases from Melanoma: In Vivo Detection with Multispectral Optoacoustic Imaging in a Mouse Model.Radiology, 280 1
E. Garai, S. Sensarn, C. Zavaleta, Dominique Sompel, N. Loewke, M. Mandella, S. Gambhir, C. Contag (2013)
High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope deviceJournal of Biomedical Optics, 18
A. Beljebbar, S. Dukic, Nadia Amharref, M. Manfait (2010)
Ex vivo and in vivo diagnosis of C6 glioblastoma development by Raman spectroscopy coupled to a microprobeAnalytical and Bioanalytical Chemistry, 398
J. Shinoda, H. Yano, S. Yoshimura, A. Okumura, Y. Kaku, T. Iwama, N. Sakai (2003)
Fluorescence-guided resection of glioblastoma multiforme by using high-dose fluorescein sodium. Technical note.Journal of neurosurgery, 99 3
Kircher (2012)
10.1038/nm.2721Nat. Med., 18
Rui Li, Ke Zheng, C. Yuan, Zhuo Chen, Mingdong Huang (2017)
Be Active or Not: the Relative Contribution of Active and Passive Tumor Targeting of NanomaterialsNanotheranostics, 1
Michael Knauth, Nurdagül Aras, C. Wirtz, Arnd Dörfler, T. Engelhorn, Klaus Sartor (1999)
Surgically induced intracranial contrast enhancement: potential source of diagnostic error in intraoperative MR imaging.AJNR. American journal of neuroradiology, 20 8
C. Kut, K. Chaichana, Jiefeng Xi, S. Raza, X. Ye, E. McVeigh, F. Rodriguez, A. Quiñones‐Hinojosa, Xingde Li (2015)
Detection of human brain cancer infiltration ex vivo and in vivo using quantitative optical coherence tomographyScience Translational Medicine, 7
S. Kantelhardt, H. Diddens, J. Leppert, V. Rohde, G. Hüttmann, A. Giese (2008)
Multiphoton excitation fluorescence microscopy of 5‐aminolevulinic acid induced fluorescence in experimental gliomasLasers in Surgery and Medicine, 40
M. Knauth, C. Wirtz, N. Aras, K. Sartor (2001)
Low-field interventional MRI in neurosurgery: finding the right dose of contrast mediumNeuroradiology, 43
Knieling (2017)
10.1056/NEJMc1612455N. Engl. J. Med., 376
A. Thakor, S. Gambhir (2013)
Nanooncology: The future of cancer diagnosis and therapyCA: A Cancer Journal for Clinicians, 63
Lene Uhrbom, E. Holland (2001)
Modeling Gliomagenesis with Somatic Cell Gene Transfer using Retroviral VectorsJournal of Neuro-Oncology, 53
S. Harmsen, M. Wall, Ruimin Huang, M. Kircher (2017)
Cancer imaging using surface-enhanced resonance Raman scattering nanoparticlesNature Protocols, 12
S. Toms (2005)
Intraoperative Optical Spectroscopy Identifies Infiltrating Glioma Margins with High SensitivityOperative Neurosurgery, 57
Jing Wang, Xie Yadian, Liming Wang, Jinglong Tang, Jiayang Li, D. Kocaefe, Y. Kocaefe, Zhiwen Zhang, Yaping Li, Chunying Chen (2015)
In vivo pharmacokinetic features and biodistribution of star and rod shaped gold nanoparticles by multispectral optoacoustic tomographyRSC Advances, 5
C. Brennan, R. Verhaak, A. McKenna, B. Campos, H. Noushmehr, S. Salama, Siyuan Zheng, D. Chakravarty, J. Sanborn, Samuel Berman, R. Beroukhim, Brady Bernard, Chang-Jiun Wu, G. Genovese, I. Shmulevich, J. Barnholtz-Sloan, L. Zou, Rahulsimham Vegesna, S. Shukla, G. Ciriello, W. Yung, Wei Zhang, C. Sougnez, T. Mikkelsen, K. Aldape, D. Bigner, Erwin Meir, M. Prados, A. Sloan, K. Black, J. Eschbacher, G. Finocchiaro, W. Friedman, D. Andrews, A. Guha, M. Iacocca, B. O'neill, G. Foltz, J. Myers, D. Weisenberger, R. Penny, R. Kucherlapati, C. Perou, D. Hayes, R. Gibbs, M. Marra, G. Mills, E. Lander, P. Spellman, R. Wilson, C. Sander, J. Weinstein, M. Meyerson, S. Gabriel, P. Laird, D. Haussler, G. Getz, L. Chin (2014)
The Somatic Genomic Landscape of GlioblastomaCell, 157
Difficulty in visualizing glioma margins intraoperatively remains a major issue in the achievement of gross total tumor resection and, thus, better clinical outcome of glioblastoma (GBM) patients. Here, the potential of a new combined optical + optoacoustic imaging method for intraoperative brain tumor delineation is investigated. A strategy using a newly developed gold nanostar synthesis method, Raman reporter chemistry, and silication method to produce dual‐modality contrast agents for combined surface‐enhanced resonance Raman scattering (SERRS) and multispectral optoacoustic tomography (MSOT) imaging is devised. Following intravenous injection of the SERRS‐MSOT‐nanostars in brain tumor bearing mice, sequential MSOT imaging is performed in vivo and followed by Raman imaging. MSOT is able to accurately depict GBMs three‐dimensionally with high specificity. The MSOT signal is found to correlate well with the SERRS images. Because SERRS enables uniquely sensitive high‐resolution surface detection, it could represent an ideal complementary imaging modality to MSOT, which enables real‐time, deep tissue imaging in 3D. This dual‐modality SERRS‐MSOT‐nanostar contrast agent reported here is shown to enable high precision depiction of the extent of infiltrating GBMs by Raman‐ and MSOT imaging in a clinically relevant murine GBM model and could pave new ways for improved image‐guided resection of brain tumors.
Small – Wiley
Published: Jan 1, 2018
Keywords: ; ; ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.