Double layered stents for carotid angioplasty: A meta‐analysis of available clinical data

Double layered stents for carotid angioplasty: A meta‐analysis of available clinical data INTRODUCTIONProcedural and post‐procedural cerebral ischemic events still represent the Achilles heel of carotid artery stenting (CAS) . While the occurrence of periprocedural events has almost been annulled by the use of embolic protection device (EPD), tailored to specific anatomic and clinical characteristics , large‐scale clinical data showed that, after the first 30 days, postprocedural ipsilateral stroke still account for a significant proportion of all CAS‐related adverse events (i.e., 0.4% per year) and this phenomenon could be related to plaque protrusion through stent struts, which occurs in more than half of the cases .Recently, the risk of post‐procedural adverse cerebral event has been linked to the size of the carotid stent free cell area indicating a robust impact of the carotid stent design on CAS outcome . The need for an increase plaque coverage to decrease the risk of debris dislodgement through the stent struts has brought to the design of a new generation of dual layered carotid stents. These devices basically consist of novel thin strut nitinol stent combined with mesh covering (which can be made of nitinol or of polyethylene terephthalate (PET) ). This design allows the device to trap and exclude thrombus and/or plaque debris so to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Catheterization and Cardiovascular Interventions Wiley
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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
1522-1946
eISSN
1522-726X
D.O.I.
10.1002/ccd.27421
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONProcedural and post‐procedural cerebral ischemic events still represent the Achilles heel of carotid artery stenting (CAS) . While the occurrence of periprocedural events has almost been annulled by the use of embolic protection device (EPD), tailored to specific anatomic and clinical characteristics , large‐scale clinical data showed that, after the first 30 days, postprocedural ipsilateral stroke still account for a significant proportion of all CAS‐related adverse events (i.e., 0.4% per year) and this phenomenon could be related to plaque protrusion through stent struts, which occurs in more than half of the cases .Recently, the risk of post‐procedural adverse cerebral event has been linked to the size of the carotid stent free cell area indicating a robust impact of the carotid stent design on CAS outcome . The need for an increase plaque coverage to decrease the risk of debris dislodgement through the stent struts has brought to the design of a new generation of dual layered carotid stents. These devices basically consist of novel thin strut nitinol stent combined with mesh covering (which can be made of nitinol or of polyethylene terephthalate (PET) ). This design allows the device to trap and exclude thrombus and/or plaque debris so to

Journal

Catheterization and Cardiovascular InterventionsWiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

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