IntroductionOne of the main routes of metastatic dissemination of melanoma is locoregional, mainly lymphatic. It is common to find a suspicious lymph node during radiological or clinical follow‐up. Histological confirmation of the malignant nature of the lymph node is required before performing a lymphadenectomy, which is associated with significant morbidity, or the implementation of systemic antitumor therapies. This evidence can be given either in the operating room under general or local anesthesia using targeted surgical adenectomy, with or without frozen sections, or through ambulatory external lymph node biopsy (ELB) with a needle or biopsy gun, with or without ultrasound guidance.Regardless of how it is conducted, ELB (fine‐needle aspiration biopsy or needle core biopsy) is a simple, rapid, and validated procedure for histological confirmation of metastatic lymph node localization of melanoma. Thus, to prove metastatic lymph node status, both techniques are validated. However, it seems logical to ask the question regarding the safety of lymph node biopsy, in particular, on the notion of extracapsular extension (ECE) in melanoma.The risk of local complication, and more specifically, seeding along the puncture path after ELB or primary tumor biopsy, has been reported or evoked in several cancers: in sarcoma, mesothelioma, hepatocellular carcinoma, and
International Journal of Dermatology – Wiley
Published: Jan 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
All the latest content is available, no embargo periods.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud