Differences in innervated neurons of the internal anal sphincter based on age and sex: A histological study

Differences in innervated neurons of the internal anal sphincter based on age and sex: A... IntroductionFecal incontinence is a relatively common anorectal disorder, with an incidence ranging from 11 to 15% according to research of a community‐based sample of adults. Many reports have shown that age is a risk factor for fecal incontinence. The incidence of fecal incontinence based on sex is controversial. Some reports have stated that there is no difference in fecal incontinence between men and women. In contrast, other reports have suggested that fecal incontinence is more common in women than in men. However, examination of anal function using manometry has shown a difference in fecal incontinence associated with age, as well as sex. Some morphological changes, such as tearing of muscle fibers during childbirth and an increase in thickness of the anal sphincter muscle as a result of aging, might explain differences in anal function.In recent years, introduction of sacral nerve stimulation, a novel treatment method for fecal incontinence, has drawn attention to the underlying neuronal pathology of fecal incontinence. As shown by the efficacy of neural mediation, anal sphincter hypofunction appears to be caused by changes not only in the muscle tissue, but also in the neurons controlling the anal sphincter. Several reports have shown that the amount of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Geriatrics & Gerontology International Wiley

Differences in innervated neurons of the internal anal sphincter based on age and sex: A histological study

Loading next page...
 
/lp/wiley/differences-in-innervated-neurons-of-the-internal-anal-sphincter-based-JYZBKM5CCW
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Japan Geriatrics Society
ISSN
1444-1586
eISSN
1447-0594
D.O.I.
10.1111/ggi.13193
Publisher site
See Article on Publisher Site

Abstract

IntroductionFecal incontinence is a relatively common anorectal disorder, with an incidence ranging from 11 to 15% according to research of a community‐based sample of adults. Many reports have shown that age is a risk factor for fecal incontinence. The incidence of fecal incontinence based on sex is controversial. Some reports have stated that there is no difference in fecal incontinence between men and women. In contrast, other reports have suggested that fecal incontinence is more common in women than in men. However, examination of anal function using manometry has shown a difference in fecal incontinence associated with age, as well as sex. Some morphological changes, such as tearing of muscle fibers during childbirth and an increase in thickness of the anal sphincter muscle as a result of aging, might explain differences in anal function.In recent years, introduction of sacral nerve stimulation, a novel treatment method for fecal incontinence, has drawn attention to the underlying neuronal pathology of fecal incontinence. As shown by the efficacy of neural mediation, anal sphincter hypofunction appears to be caused by changes not only in the muscle tissue, but also in the neurons controlling the anal sphincter. Several reports have shown that the amount of

Journal

Geriatrics & Gerontology InternationalWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial