Diet and IVF pilot study: Short‐term weight loss improves pregnancy rates in overweight/obese women undertaking IVF

Diet and IVF pilot study: Short‐term weight loss improves pregnancy rates in overweight/obese... Obesity worsens and modest weight loss improves female fertility. Overweight women were randomised to lifestyle or standard treatment pre‐in vitro fertilisation with treatment cessation at embryo transfer. There was a greater reduction in weight (P < 0.001) for lifestyle treatment (−3.8 ± 3.0 kg, P < 0.001) compared with no changes for standard treatment (−0.5 ± 1.2 kg, P = 0.092). Both the intervention (−5.3 ± 4.6 cm) and control (−3.5 ± 3.5 cm) group had reductions in waist circumference (P < 0.001) with no differences between the two groups (P = 0.215). The overall pregnancy rate was 53% (20/38) for the intervention and control group combined. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Australian and New Zealand Journal of Obstetrics and Gynaecology Wiley

Diet and IVF pilot study: Short‐term weight loss improves pregnancy rates in overweight/obese women undertaking IVF

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Publisher
Wiley
Copyright
© 2011 The Authors. Australian and New Zealand Journal of Obstetrics and Gynaecology © 2011 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists
ISSN
0004-8666
eISSN
1479-828X
D.O.I.
10.1111/j.1479-828X.2011.01343.x
Publisher site
See Article on Publisher Site

Abstract

Obesity worsens and modest weight loss improves female fertility. Overweight women were randomised to lifestyle or standard treatment pre‐in vitro fertilisation with treatment cessation at embryo transfer. There was a greater reduction in weight (P < 0.001) for lifestyle treatment (−3.8 ± 3.0 kg, P < 0.001) compared with no changes for standard treatment (−0.5 ± 1.2 kg, P = 0.092). Both the intervention (−5.3 ± 4.6 cm) and control (−3.5 ± 3.5 cm) group had reductions in waist circumference (P < 0.001) with no differences between the two groups (P = 0.215). The overall pregnancy rate was 53% (20/38) for the intervention and control group combined.

Journal

Australian and New Zealand Journal of Obstetrics and GynaecologyWiley

Published: Oct 1, 2011

References

  • Effect of prepregnancy body mass index categories on obstetrical and neonatal outcomes
    Abenhaim, Abenhaim; Kinch, Kinch; Morin, Morin
  • A pilot comprehensive lifestyle intervention program (CLIP) – Comparison with qualitative lifestyle advice and simvastatin on cardiovascular risk factors in overweight hypercholesterolaemic individuals
    Cleanthous, Cleanthous; Noakes, Noakes; Brinkworth, Brinkworth

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