Contrasting patterns and frequency of antibodies to the surface, core, and e antigens of hepatitis b virus in blood donors and in homosexual patients

Contrasting patterns and frequency of antibodies to the surface, core, and e antigens of... An attempt was made to assess the significance of the relatively frequent low‐titre positive reactions in radioimmunoassays for antibody to hepatitis B surface antigen. Serum specimens negative for surface antigen were assayed for antibodies to the surface, core, and e antigens of the Hepatitis B virus. Two populations were studied—one of low hepatitis B incidence (2000 blood donors) and one of high incidence (200 male patients attending a clinic for sexually transmitted diseases). The validity of some singly occurring low‐titre anti‐HBs and anti‐HBc reactions is questioned, and the occurrence of positive reactions unrelated to previous hepatitis B infection inferred. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Medical Virology Wiley

Contrasting patterns and frequency of antibodies to the surface, core, and e antigens of hepatitis b virus in blood donors and in homosexual patients

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Publisher
Wiley
Copyright
Copyright © 1980 Wiley‐Liss, Inc., A Wiley Company
ISSN
0146-6615
eISSN
1096-9071
DOI
10.1002/jmv.1890060407
Publisher site
See Article on Publisher Site

Abstract

An attempt was made to assess the significance of the relatively frequent low‐titre positive reactions in radioimmunoassays for antibody to hepatitis B surface antigen. Serum specimens negative for surface antigen were assayed for antibodies to the surface, core, and e antigens of the Hepatitis B virus. Two populations were studied—one of low hepatitis B incidence (2000 blood donors) and one of high incidence (200 male patients attending a clinic for sexually transmitted diseases). The validity of some singly occurring low‐titre anti‐HBs and anti‐HBc reactions is questioned, and the occurrence of positive reactions unrelated to previous hepatitis B infection inferred.

Journal

Journal of Medical VirologyWiley

Published: Jan 1, 1980

References

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