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Contrast‐enhanced power Doppler sonography: Improved detection of characteristic flow patterns in focal liver lesions

Contrast‐enhanced power Doppler sonography: Improved detection of characteristic flow patterns in... Purpose The aim of this study was to evaluate whether intravenous injection of an ultrasound contrast agent aids in the visualization of focal liver lesions on power Doppler images. Methods Fifty patients with focal liver lesions were studied by B‐mode and power Doppler sonography before and after intravenous injection of the contrast agent Levovist (galactose‐based microbubbles; 10 ml of a concentration of 300 mg/ ml). Thirty‐two patients had malignant liver lesions (19 metastases, 12 hepatocellular carcinomas, 1 cholangiocellular carcinoma), while 18 had benign lesions (12 hemangiomas, 2 focal nodular hyperplasias, 4 others). Results After contrast medium injection, the number of lesions with no intralesional flow dropped from 18 to 9. Flow signal intensity was rated subjectively as marked on contrast‐enhanced images in 17 patients; only 4 patients had marked flow on precontrast images. On precontrast studies, central flow in 10 lesions and peripheral flow in 29 lesions could be observed. After enhancement, the numbers increased to 18 and 34 lesions, respectively. Conclusions On power Doppler images, a greater number of intratumoral vessels are seen in focal liver lesions after contrast medium administration. © 1999 John Wiley & Sons, Inc. J Clin Ultrasound 27:107–115, 1999. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Clinical Ultrasound Wiley

Contrast‐enhanced power Doppler sonography: Improved detection of characteristic flow patterns in focal liver lesions

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References (16)

Publisher
Wiley
Copyright
Copyright © 1999 John Wiley & Sons, Inc.
ISSN
0091-2751
eISSN
1097-0096
DOI
10.1002/(SICI)1097-0096(199903/04)27:3<107::AID-JCU2>3.0.CO;2-Y
Publisher site
See Article on Publisher Site

Abstract

Purpose The aim of this study was to evaluate whether intravenous injection of an ultrasound contrast agent aids in the visualization of focal liver lesions on power Doppler images. Methods Fifty patients with focal liver lesions were studied by B‐mode and power Doppler sonography before and after intravenous injection of the contrast agent Levovist (galactose‐based microbubbles; 10 ml of a concentration of 300 mg/ ml). Thirty‐two patients had malignant liver lesions (19 metastases, 12 hepatocellular carcinomas, 1 cholangiocellular carcinoma), while 18 had benign lesions (12 hemangiomas, 2 focal nodular hyperplasias, 4 others). Results After contrast medium injection, the number of lesions with no intralesional flow dropped from 18 to 9. Flow signal intensity was rated subjectively as marked on contrast‐enhanced images in 17 patients; only 4 patients had marked flow on precontrast images. On precontrast studies, central flow in 10 lesions and peripheral flow in 29 lesions could be observed. After enhancement, the numbers increased to 18 and 34 lesions, respectively. Conclusions On power Doppler images, a greater number of intratumoral vessels are seen in focal liver lesions after contrast medium administration. © 1999 John Wiley & Sons, Inc. J Clin Ultrasound 27:107–115, 1999.

Journal

Journal of Clinical UltrasoundWiley

Published: Mar 1, 1999

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