What's new?‐The CONCEPTT trial showed that real‐time continuous glucose monitoring (CGM) was associated with improvements in maternal glycaemic control and in neonatal health outcomes.‐The number‐needed‐to‐treat with CGM to prevent large‐for‐gestational‐age infants or neonatal intensive care unit admission >24 h was six, and to prevent a case of neonatal hypoglycaemia it was eight.‐Further issues include the use of newer technologies with improved patient satisfaction, and closed‐loop therapy may further improve outcomes.‐High rates of large infants despite treatment remain a challenge, and future investigations must assess the impact of dietary factors, glucose variability and information gleaned from metabolomics.IntroductionDiabetes is the commonest pre‐existing medical condition in pregnancy, affecting 1.5% of pregnancies . Approximately half of all pregnancies in women with pre‐existing diabetes are complicated by Type 1 diabetes, and the remainder by Type 2 diabetes and other forms of monogenic diabetes . The prevalence of Type 1 diabetes in young people has doubled in the past two decades, meaning that in the future even more women will enter pregnancy with potentially more complicated Type 1 diabetes and diabetes of longer duration . National audit data highlight the prevalence of suboptimal control of maternal glucose levels before and during pregnancy . The most
Diabetic Medicine – Wiley
Published: Jan 1, 2018
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