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Contact allergy to preservatives – II

Contact allergy to preservatives – II To determine whether the prevalence of allergic reactions to certain preservatives warrants their inclusion in a routine series for patch testing, a tray of 14 preservatives was tested in 501 consecutive suspected contact dermatitis patients. More than l% positive reactions were found with DMDM hydantoin. Kathon CG® and alkyl trimethyl ammonium chloride only. The concentration of alkyl trimethyl ammonium chloride (0.1% aqua) was considered too high. Of 6 patients reacting to the formaldehyde releaser DMDM hydantoin. 4 were positive to formaldehyde. Kathon CG® may be an important allergen in the Netherlands, and it is worthwhile for dermatologists there to add it to the standard test series. The recent inclusion afquaternium‐15 in the ICDRG standard series appears to be of little value to them. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Contact Dermatitis Wiley

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Publisher
Wiley
Copyright
Copyright © 1986 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0105-1873
eISSN
1600-0536
DOI
10.1111/j.1600-0536.1986.tb01340.x
Publisher site
See Article on Publisher Site

Abstract

To determine whether the prevalence of allergic reactions to certain preservatives warrants their inclusion in a routine series for patch testing, a tray of 14 preservatives was tested in 501 consecutive suspected contact dermatitis patients. More than l% positive reactions were found with DMDM hydantoin. Kathon CG® and alkyl trimethyl ammonium chloride only. The concentration of alkyl trimethyl ammonium chloride (0.1% aqua) was considered too high. Of 6 patients reacting to the formaldehyde releaser DMDM hydantoin. 4 were positive to formaldehyde. Kathon CG® may be an important allergen in the Netherlands, and it is worthwhile for dermatologists there to add it to the standard test series. The recent inclusion afquaternium‐15 in the ICDRG standard series appears to be of little value to them.

Journal

Contact DermatitisWiley

Published: Sep 1, 1986

References